Nano Initiative: The Single-Molecule DNA Transistor

丽迪亚·索恩普林斯顿大学纳米探索性研究：单分子DNA转移这个项目的重点是探索将单分子DNA用于基于分子的电子器件的可能性。单分子DNA晶体管的最新结果表明，库仑阻塞阶梯和栅极电压依赖于电导，从而实现了可靠和可重复的导电DNA器件。该项目正在进一步研究DNA传导的机制及其对各种化学和结构参数的依赖。单分子DNA晶体管正在被进一步研究，以了解DNA传导的机制。各种问题，如DNA的电导率与长度和序列的依赖关系；单链和双链DNA之间的电导差异；DNA分子中的电导对缓冲溶液中的盐的依赖关系；DNA分子中可能的散射中心位于哪里？对这些基本问题的回答有望导致未来一些基于DNA的新型分子规模电子设备的出现。

EIA-0103215Lydia SohnPrinceton UniversityNano Exploratory Research: The Single-Molecule DNA TransferThe focus of this project is to investigate the possibility of using single molecules of DNA for molecular-based electronic devices. Recent results of single-molecule DNA transistor shows a Coulomb Blockade Staircase and a gate-voltage dependence of the conductance enabling reliable and reproducible conducting DNA devices. This project is furthering this work to investigate the mechanism for DNA conduction and its dependence on various chemical and structural parameters. The single-molecule DNA transistor is being further investigated too understand the mechanism by which DNA conducts. Various questions such as dependence of conductivity of DNA to length and sequence; differences in conductivity between single-stranded and doubled-stranded DNA; dependence of the conduction in DNS to salts from the buffer solution; where are possible scattering centers located in the DNA molecule? Answers to such fundamental questions are expected to lead to a number of future novel molecular-scaled DNA-based electronic devices.