Postdoctoral Research Fellowship in Biological Informatics for FY2001

这一行动为NSF 2001财年生物信息学博士后研究奖学金提供了资金。该奖学金支持生物学与信息科学、计算科学、数学科学和统计科学交叉的博士后水平的研究和培训。该研究金的目标是为一名青年科学家提供培训，为从事生物信息学的职业做准备，在生物信息学中将把研究和教育结合起来。各个职业层次对生物信息学的培训需求日益增加，预计通过这些奖学金培训的研究员将在未来的劳动力培训中发挥重要作用。该奖学金的研究和培训计划题为“探索基因序列、蛋白质形式和功能的系统发育趋势，以了解分子进化过程”。光合作用基因rbcL和一个大型系统发育图正被用来将分子选择联系起来，将基因序列与蛋白质的形式和功能联系起来。进化趋势正被用来揭示分子选择的模式，这些模式本来是看不见的，并有助于产生关于基因-蛋白质关系的可行理论。这项研究的重点是开发普遍适用的基因和蛋白质进化模型，并提供信息工具来质疑其他基因和系统中的分子选择过程。

This action funds an NSF Postdoctoral Research Fellowship in Biological Informatics for FY2001. The fellowship supports research and training at the postdoctoral level at the intersection of biology and the informational, computational, mathematical, and statistical sciences. The goal of the fellowship is to provide training to a young scientist in preparation for a career in biological informatics in which research and education will be integrated. There is an increasing need for training in biological informatics at all occupational levels, and it is expected that Fellows trained through these fellowships will play important roles in training of the future workforce.The research and training plan for this fellowship is entitled "Exploring phylogenetic trends of gene sequence, protein form and function to comprehend processes of molecular evolution." The photosynthetic gene rbcL and a large phylogeny are being used to link molecular selection linking gene sequence to protein form and function. Evolutionary trends are being used to reveal patterns of molecular selection that are otherwise invisible and are helping to generate viable theories about gene-protein relationships. The research is focused on developing generally applicable models of gene and protein evolution and providing informatic tools to question processes of molecular selection in other genes and systems.