CRCD: From Sequence to Expression and Structure: An Innovative Research-Oriented Course

0203396Marek KimmelWilliam Marsh Rice大学生物信息学：从序列到表达和结构。“这个项目的主要目标是教高级学生如何研究计算生物学中的前沿问题。该项目涉及开发和传播直接基于领先的多学科研究的创新课程。知道如何识别和解决主要研究问题的毕业生将获得能够将生物信息学应用于广泛问题的显着好处。除了沉浸在蓬勃发展的研究领域之外，该计划的毕业生可以免费获得该领域发展的最新知识和技能，可以在劳动力中享有竞争优势。为了培养能够领导独立研究的学生，该项目侧重于三个教育成果：1。学生在这一领域发展解决科学和数学问题的元认知知识。他们获得了基因组和后基因组研究的领先生物信息学模型和研究方法的集成知识库。学生在个人和多学科团队中都能提高工作能力。为了达到这些目标，该项目为高年级本科生或研究生开设了一门生物信息学课程，该课程将前沿研究相关内容与新颖独特的教学、评估和传播手段相结合。本课程的长期目标与学生未来的职业生涯有关。工商界和学术界的生物信息学前沿研究已经从DNA序列水平转向对基因表达和相互作用以及生物分子相互作用的探索。参加本课程的学生将对生物信息学研究和计算生物学有较高的理解。

0203396Marek KimmelWilliam Marsh Rice University"Bioinformatics: From Sequence to Expression and Structure. An Inovative Research-Oriented Course"The primary goal of this project is to teach advanced students how to investigate cutting-edge problems in computational biology. The project involves developing and disseminating an innovative course based directly upon leading multidisciplinary research. Graduates who know how to identify and work on solving leading research problems gain the significant benefit of being able to apply bio-informatics to a broad range of problems. In addition to being immersed in a burgeoning research sector, graduates of this program, who have free access to the newest knowledge and skills in the field as it evolves, may enjoy a competitive advantage in the workforce. To produce students capable of leading independent research, the project focuses on three educational outcomes: 1. Students develop meta-cognitive knowledge of scientific and mathematical problem solving in this field, 2. They acquire an integrated knowledge base of leading bio-informatics models and research methods for genomic and post-genomic research, and finally, 3. Students improve at working both as individuals and in multidisciplinary teams. To reach these objectives, the project presents a course in bio-informatics, on a senior undergraduate or graduate level, which integrates cutting-edge research-related content with novel and unique means of teaching, evaluation and dissemination. The long-term goal of the course is related to prospective professional careers of students. The cutting-edge bio-informatics research in industry and academia already is shifting from the DNA sequence level to exploration of gene expression and interaction and bio-molecular interactions. Students enrolled in the proposed course will develop a high level understanding of bio-informatics research and computational biology.