MR-PET für medizinische Bildgebung

当将正电子发射断层扫描(PET)和磁共振成像(MRL)集成到一个成像系统中时，必须解决几个技术和临床问题。在第一步中，本研究项目旨在评估PET与MRL的相互作用。工作时间表的这一主要技术部分将解决磁共振设备(如射频接收器线圈或造影剂)对PET衰减校正的潜在影响，评估呼吸或植入物造成的潜在伪影，并评估与非511keV发射器的衰减校正有关的具体问题。将针对这些相互作用机制制定解决方案。此外，该研究项目旨在确定MR-PET的临床适应症，并将MR-PET应用于临床常规。该小组将开发适用于各种肿瘤和心血管适应症的MR-PET扫描方案，并将这些方案转移到常规诊断成像。一旦临床可行的扫描方案被开发并在临床上实施，该研究项目旨在评估MR-PET对各种恶性疾病和心血管混合成像的诊断准确性。

When integrating Positron Emission Tomography(PET) and Magnetic Resonancle Imaging (MRl) into one imaging systems, several technical and clinical questions have to be addressed. In a tirst step, this research project aims at assessing the interaction of PET with MRl. This mainly technical part of the work schedule will address potential effects of MR equipment (such as radiofrequency receiver coils or contrast agents) on PET attenuation correction, evaluate potential artefacts caused by breathing or implants, and assess specific questions pertaining to attenuation correction in non-511 keV emitters. Solutions to these mechanisms of interaction will be developed. Furthermore, the research project aims at defining clinical indications for MR-PET and at implementing MR-PET into clinical routine. The group will develop MR-PET scanning protocols for various oncological and cardiovascular indications and will transfer these protocolls to routine diagnostic imaging. Once clinically feasible scanning protocols have been developed and implemented clinically, the research project aims at assessing the diagnostic accuracy of MR-PET with regard to various malignant diseases and cardiovascular hybrid imaging.