Boronate-Linked Extended Polymer Networks

有机和高分子化学计划支持南卡罗来纳州大学化学系的John Lavigne教授，他在自组装硼酸盐连接的超分子网络方面的工作，这代表了设计分子聚集体的新范式。所提出的系统是基于共价但可逆的硼酸酯的形成，利用三角平面硼化合物和二醇化合物在非水介质中，在结构单元之间形成硼酸酯。这种方法与大多数关于硼酸/酯平衡的分子识别文献相反，该文献侧重于两个分子单元的组装。考虑到硼酸酯形成的共价可逆性质，这些组装体应以高度有序的方式形成。这些多孔网络将仍然保持其结构完整性，即使没有获得结晶材料。预计这些组件将在其他自组装网络预测的任何应用中找到实用性。然而，考虑到组装机制的性质，将预期改进的稳定性和因此增强的性质。与它们的共价键合的有机对应物相比，硼酸酯连接的超分子应该以更容易和更高的效率组装;与非共价键合的等价物（例如氢键合）相比，硼酸酯连接的材料应该显示出增强的稳定性，给出更强的分子间相互作用。此外，这种相互作用的方向性和选择性将允许引入额外的功能，从而创造明确的，高度官能化的material.With这个奖项，有机和高分子化学计划支持约翰·拉维尼教授在南卡罗来纳州的研究活动，重点是硼酸酯连接网络的合成和表征。组装策略可以扩展到导致新的纳米尺度材料的开发，用于分离、传感、催化、化学和信息存储领域的潜在应用，如光子材料，以及丰富的其他实际应用。学生将接触到广泛的主题，包括有机化学，物理化学和超分子材料。学生将在高度多学科的环境中接受培训，并为聚合物、制药和分析化学领域的研究职业做好准备。

The Organic and Macromolecular Chemistry Program support Professor John Lavigne of the Department of Chemistry at the University of South Carolina, for his work on self-assembling boronate-linked supramolecular networks, which represents a new paradigm in designing molecular aggregates. The proposed systems are based on the covalent yet reversible boronate ester formation utilizing trigonal planar boron compounds and diol compounds in non-aqueous media, forming boronate esters between the building blocks. This approach is in contrast to the majority of molecular recognition literature on boronic acid/ester equilibria which focuses on the assembly of two molecular units. Given the covalent, reversible nature of the boronate ester formation, these assemblies should form in a highly ordered manner. These porous networks will still maintain their structural integrity even if crystalline materials are not obtained. These assemblies are expected to find utility in any of the applications predicted for other self-assembled networks. However, considering the nature of the assembly mechanism, improved stability and therefore enhanced properties would be expected. Compared to their covalently bonded organic counterparts, boronate-linked supramolecules should be assembled with greater ease and higher efficiency; compared to the non-covalently bonded equivalent (such as hydrogen bonding), the boronate linked materials should display enhanced stability given the stronger intermolecular interaction. Furthermore, the directionality and selectivity of this interaction will allow for the introduction of additional functionality thereby creating well-defined, highly functionalized materials.With this Award, the Organic and Macromolecular Chemistry Program supports the research activities of Professor John Lavigne at the University of South Carolina that focuses on the synthesis and characterization of the boronate-linked networks. The assembly strategy could be extended to lead to the development of new nano-scale materials for potential applications in the areas of separations, sensing, catalysis, chemical and information storage, as photonic materials, and a wealth of other practical applications. Students will be exposed to a wide range of topics including organic chemistry, physical chemistry, and supramolecular materials. Students will receive training in a highly multidisciplinary environment and will be prepared for research careers in polymers, pharmaceuticals and analytical chemistry.