U.S.-Japan Workshop: Molecular and Cellular Aspects of Vascular Smooth Muscle

OISE-0623085（韦伯，克林顿;格鲁吉亚医学院）“血管平滑肌的分子和细胞方面“摘要该奖项支持由格鲁吉亚医学院的PI及其合作者群马大学医学研究生院的Kazuhiro Kohama博士在Kailua-Kona共同组织的主题为“血管平滑肌的分子和细胞方面”的研讨会，2006年秋天的夏威夷。研讨会将有18名美国参与者，包括13名初级和高级教师和5名研究生，以及相当数量的日本科学家。参与者来自美国和日本的一小群科学家，他们的研究集中在跨物种模型中在分子和细胞水平上了解血管平滑肌的收缩活动。每位研究者将是涉及平滑肌功能收缩和舒张的四个过程之一的专家：1）膜兴奋; 2）兴奋-收缩偶联; 3）能量代谢;和4）化学机械转导。研讨会将为每一位专家提供一个机会，使他们了解目前关于其他组成部分的研究结果。此外，研讨会将讨论平滑肌收缩方面的比较生物学的两个方面：1）跨物种变异; 2）同一物种内的区域变异（即各种区域血管床）。

OISE-0623085 (Webb, Clinton; Medical College of Georgia)"Molecular and Cellular Aspects of Vascular Smooth Muscle"ABSTRACTThis award supports a workshop on the topic of "Molecular and Cellular Aspects of Vascular Smooth Muscle" to be co-organized by the PI, from the Medical College of Georgia, and his collaborator, Dr. Kazuhiro Kohama of Gunma University Graduate School of Medicine, in Kailua-Kona, Hawaii in Fall 2006. The workshop will involve 18 U.S. participants-including 13 junior and senior faculty and five graduate students-and a comparable number of Japanese scientists. Participants are drawn from a small group of scientists in the U.S. and Japan whose research concentrates on understanding the contractile activity if vascular smooth muscle at a molecular and cellular level in cross-species models. Each investigator will be an expert in one of four processes involves in contraction and relaxation of smooth muscle function: 1) membrane excitation; 2) excitation-contraction coupling; 3) energy metabolism; and 4) chemomechanical transduction. The workshop will provide an opportunity for each expert to be informed of results of current research on the other components. Additionally, the workshop will address two aspects of comparative biology with respect to smooth muscle contraction: 1) cross species variations; and 2) regional variability within the same species (i.e. various regional vascular beds).