SGER: Controlled fragmentation and ionization of biological samples

在这个由实验物理化学计划资助的SGER奖项中，密歇根州立大学的Marcos Dantus教授和他的研究生和本科生同事将进行探索性研究，试图开发气相中电离生物物种的受控碎片和检测。他们建议通过使用整形飞秒激光脉冲来实现这一点。丹图斯和他的团队将尝试使用成形的超快激光脉冲来选择性地粉碎气相中的大生物离子。这些研究的最终目的是利用可编程的激光光源获取生物大分子的结构信息。这类仪器的主要影响将是在生物研究方面。从事这项工作的研究生和本科生将在物理和生物科学的交界处接受出色的研究培训。

In this SGER award, funded by the Experimental Physical Chemistry Program, Prof. Marcos Dantus of Michigan State University and his graduate and undergraduate student colleagues will conduct exploratory research in the attempt to develop the controlled fragmentation and detection of ionized biological species in the gas phase. They propose to do this through the use of shaped femtosecond laser pulses.Prof. Dantus and his group will attempting to use shaped ultrafast laser pulses to selectively fragment large biological ions in the gas phase. The ultimate aim of these studies is to obtain structural information of large biomolecules with a programmable laser source. The major impact of this type of instrument would be in biological research. The graduate and undergraduate students working on this will receive stellar training in research that is at the interface of physical and biological science.