Targeted Infusion Grant: Enhancing the Undergraduate Biochemistry Experience by Implementing a Concentration in Biochemistry within the Chemistry Program

生物技术的进步和创新促进了北卡罗来纳州以及东海岸生物科学和生物技术中心的重大生物科学研究和商业发展。在全国范围内，生物技术的影响，特别是对人类基因组图谱和这种技术进步的应用的影响，在这个国家的经济发展中发挥了重要作用。这为化学专业的学生创造了一个扩大职业选择的机会，特别是在温斯顿-塞勒姆州立大学(WSSU)，该大学位于生物科学的主要参与者皮埃蒙特三合会地区。这个定向灌输项目的目标是在威斯康星州立大学现有的化学课程中实施生物化学专业，以增强本科生在生物化学方面的课程体验。生物科学在研究和工业中的明显影响创造了提供这种生物化学选项的需要，不仅是为了确保为学生提供跨学科的指导和研究培训，而且还为了吸引更多的少数族裔学生进入这门科学学科。这些努力还将支持该机构目前为履行其经济发展作用而采取的举措。这一有针对性的灌输项目的目标是：(I)实施美国化学学会批准的具有生物化学学科的化学学位课程；(Ii)将生物技术中的先进技术应用于生物化学实验室教学；以及(Iii)提供支持先进生物化学技术的仪器，以确保在教学、培训和研究工作中确保必要的连续不断，使学生对生物科学研究和工业中使用的技术有更多的认识。长期目标是在威斯康星州立大学建立跨学科生物化学学位。这个项目的学术价值包括使学生做好准备，以应对生化和生物研究和工业的最新趋势，为化学系的研究基础做出贡献，并进一步使学生接触到研究的跨学科性质。拟议的高级生物化学实验室纳入了绿色荧光蛋白的统一主题，最终通过圆二色谱进行结构和稳定性研究，是该项目的创新部分。实施的实验模块顺序将在高级生物化学实验室提供统一的学习体验。该项目的更广泛影响包括促进高素质学生的经济发展，以满足我们日益依赖科学技术进步的社会的需求。该项目为加强本科生生物化学经验而开发的课程改进将在适当的期刊上发表，在地方和国家会议上传播，并通过两个系的网站免费提供，以促进教学、培训和学习。WSSU STEM项目的预期结果包括增加化学和生化科学专业的毕业生人数，包括未被充分代表的少数族裔学生。

Advances and innovations in biotechnology have promoted significant bioscience research and business in the economic development of North Carolina, and the east coast bioscience and biotechnology centers. Nationwide, the impact of biotechnology, especially on the mapping of the human genome and the applications of such technological advances, has played a significant role in the economic development of this nation. This creates an opportunity to expand the career options for chemistry majors, especially at Winston-Salem State University (WSSU), which is located in the Piedmont Triad region, a major player in bioscience. The goal of this targeted infusion project is to implement a Concentration in Biochemistry within the existing chemistry program at WSSU to enhance the undergraduate curriculum in biochemistry experience. The evident impact of bioscience in research and industry creates a need to offer this biochemistry option not only to ensure interdisciplinary instructions and research training for students, but also to attract more minority students to this scientific discipline. These efforts will also support current initiatives at this institution to fulfill its economic development role. The objectives of this targeted infusion project are; (i) to implement an ACS-Approved Chemistry degree program with a Biochemistry Track, (ii) to adapt and integrate advanced techniques in biotechnology into the biochemistry laboratory instructions, and (iii) to provide instrumentation to support advanced biochemistry techniques that will secure the necessary continuum in instruction, training, and research efforts, for preparing students to be more perceptive to techniques used in bioscience research and industry. The long term goal is to establish an interdisciplinary biochemistry degree offering at WSSU. The intellectual merits of this project include preparing students in response to recent trends in biochemical and biological research and industry, contribute to the research base at the Chemistry Department, and further expose students to the interdisciplinary nature of research. The proposed advanced biochemistry laboratory incorporating a unifying theme on the green fluorescent protein culminating in the structural and stability studies by Circular Dichroism is an innovative part of this project. The modular sequence of the implemented experiments will provide a unified learning experience in the advanced biochemistry laboratory. The broader impacts of this project include the promotion of economical development in quality students to meet the needs of our society, which is increasingly dependent on advances made in science and technology. The curricular enhancement developed in this project to strengthen the undergraduate biochemistry experience will be published in appropriate journals, disseminated at local and national meetings, and made freely available via websites of both departments to promote teaching, training, and learning. An anticipated outcome of this project on the STEM program at WSSU includes an increase in the number of graduates, including underrepresented minority students, in the chemical and biochemical sciences.