The International Neuroinformatics Coordinating Facility: Cyber-infrastructure for Global Neuroinformatics

[0733492]这项非研究奖为总部设在瑞典斯德哥尔摩的多边组织国际神经信息学协调机构（INCF）的成员提供了四年的美国支持。INCF是一项协调的国际科学努力，旨在为导航和整合神经科学不同领域内的分布式资源创建门户。到目前为止，有13个国家（比利时、捷克共和国、芬兰、法国、德国、意大利、日本、荷兰、挪威、瑞典、瑞士、英国和美国）和欧盟委员会是成员国。计算机科学中心提供的新服务将有助于改进数据的获取和整合以及组织各级之间知识的转移，并有助于更迅速地发展切合实际的大脑功能模型。INCF的神经信息社区门户将提供神经科学数据库和相关软件工具的可互操作网络。此外，INCF将提供经过测试和验证的工作流程，定义输入和输出，以及使用这些工作流程进行数据分析的教程和说明。最初的四年将集中在神经系统的大规模建模，小鼠和大鼠大脑的数字图谱，fMRI数据资源的整合，以及神经解剖学的命名和分类。更广泛的影响：为了社会的长期利益，脑和神经系统研究需要整合在多个调查层面收集的异构和复杂的数据。这种能力由INCF提供，这是一个重要的全球网络，旨在促进对基本脑功能、神经系统毁灭性疾病以及应用于信息科学和人工系统开发的神经处理的知识和理解。INCF是一个新颖的，国际资助的基础设施，利用神经信息学的多个层次的专业知识-跨越边界，科学领域，私营和公共部门，方法和方法。

0733492BjaalieThis non-research award provides four years of U.S. support for membership in the International Neuroinformatics Coordinating Facility (INCF), a multilateral organization headquartered in Stockholm, Sweden. INCF is a coordinated, international scientific effort to create a portal for navigation and integration of distributed resources within different domains of neurosciences. Thirteen nations so far (Belgium, Czech Republic, Finland, France, Germany, Italy, Japan, Netherlands, Norway, Sweden, Switzerland, United Kingdom, and the United States) and the European Commission are members. The new services provided by INCF will contribute to improved access and integration of data and transfer of knowledge between levels of organization, and a more rapid development of realistic models of brain functions. INCF's Neuroinformation Community Portal will provide an interoperable network of neuroscience databases and related software tools. In addition, INCF will offer tested and validated work flows, with defined inputs and outputs, and tutorials and instructions for making use of such work flows for data analysis. The initial four years will concentrate on large-scale modeling of the nervous system, mouse and rat brain digital atlasing, integration of fMRI data resource, and neuroanotomical nomenclature and taxonomy. Broader Impacts: Brain and nervous system studies for the long-term benefit of society require integration of heterogeneous and complex data collected at multiple levels of investigation. That capability is provided by INCF, a critical global network to advance knowledge and understanding of basic brain functions, devastating diseases of the nervous system, and neural processing as applied to information sciences and development of artificial systems. The INCF is a novel, internationally-funded infrastructure taking advantage of multiple levels of expertise in neuroinformatics - across boundaries, scientific domains, private and public sectors, methodologies and approaches.