CAREER: Macromolecular Materials Based on the Diverse Chemistry of Arylboronic Acids and Arylboroxines

有了这个职业奖，有机和大分子化学项目支持圣地亚哥大学Peter Iovine教授的研究。Iovine教授将把芳基硼酸和芳基硼氧酮的不同化学性质应用于新材料的合成。首先，将开发一种操作简单的合成方法来合理控制芳基硼氧化合物的取代模式。其次，将小分子芳硼胺化学应用于含三足芳硼胺核的Lewis酸性树状大分子的合成。树状大分子是由单个粘性末端树突的脱水缩合形成的，这些树突的焦点上有一个单一的芳基硼酸官能团。研究了Lewis碱客体分子与反应核的可逆结合以及这些客体在树状聚合物中的迁移。在最终目标中，硼酸尖端树突将被用作大分子试剂来化学修饰可再生材料。艾欧文教授还将启动两个研究与教学相结合的教育项目。第一个项目涉及针对两所当地学校的外展计划，这两所学校主要服务于代表性不足的群体。在与当地教育工作者建立工作关系后，Iovine教授将设计并教授一门课程，为本科科学专业的学生探索与科学推广相关的社会影响和最佳实践。第二项教育举措是将教师或工业合作伙伴的研究融入高年级的讲座/实验课程。一个学期的三分之一将用于由系内教师或当地行业合作伙伴培养的开放式研究项目。

With this CAREER Award, the Organic and Macromolecular Chemistry program is supporting the research of Professor Peter Iovine of the University of San Diego. Professor Iovine will apply the diverse chemistry of arylboronic acids and arylboroxines to the synthesis of new materials. First, an operationally simple synthetic methodology will be developed to rationally control the substitution pattern in arylboroxine compounds. Second, small molecule arylboroxine chemistry will be applied to the synthesis of Lewis acidic dendrimers containing tripodal arylboroxine cores. The dendrimers are formed by the dehydration condensation of individual sticky-ended dendrons, which have at their focal point, a single arylboronic acid functional group. The reversible binding of Lewis basic guest molecules to the reactive core as well as the migration of these guests in and out of the dendrimer will be studied. In the final objective, boronic acid-tipped dendrons will be used as macromolecular reagents to chemically modify renewable materials.Professor Iovine will also initiate two educational projects that interweave research and teaching. The first project involves an outreach program targeting two local schools that serve predominantly underrepresented groups. After establishing working relationships with the local educators, Professor Iovine will design and teach a course to undergraduate science majors exploring the societal implications and best practices associated with scientific outreach. The second educational initiative infuses faculty or industrial partner research into upper-division lecture/laboratory courses. One third of a semester will be devoted to open-ended research projects that are cultivated from Departmental faculty or local industry partners.