International Collaboration in Chemistry: Redox Control of Chemical Bond Forming Reactions

这个国际奖项由无机，生物无机和有机化学计划和国际科学与工程办公室（OISE）在美国国家科学基金会和德国研究共同体（DFG）在德国支持教授大卫A。夏威夷大学的Vicic，开发了使用单电子氧化还原过程形成化学键的新方法。 研究人员将合理地操纵烷基-烷基交叉偶联反应，以便形成新的饱和碳-碳键。 三联吡啶基镍配合物的光谱电化学分析正在催化相关的条件下进行研究，并将探索催化规模的电催化交叉偶联反应。 德国科隆大学的阿克塞尔克莱因教授将在电子顺磁共振（EPR）光谱测量和光谱电化学研究方面进行合作。 美国研究生将在他的实验室接受培训。 引进一种新的EPR光谱仪（由夏威夷大学共同资助）将是该州独一无二的，并将大大加强这个地理位置偏远地区的基础设施。 烷基-烷基交叉偶联反应代表了高风险/高回报化学，其在合成饱和碳-碳键（制药和化学工业的重要原料）中可能发挥关键作用。

This international award by the Inorganic, Bioinorganic and Organometallic Chemistry Program and the Office of International Science and Engineering (OISE) at NSF and the Deutsche Forschungsgemeinschaft (DFG) in Germany supports Professor David A. Vicic of the University of Hawaii for the development of new methods of chemical bond formation using one-electron redox processes. The researchers will rationally manipulate alkyl-alkyl cross coupling reactions so that new, saturated carbon-carbon bonds can be formed. The spectroelectrochemical analyses of terpyridine-based nickel complexes are being studied under catalytically-relevant conditions and preparative-scale, electrocatalytic cross-coupling reactions will be explored. Professor Axel Klein of the University of Cologne in Germany will collaborate on electron paramagnetic resonance (EPR) spectroscopy measurements and spectroelectrochemical studies. U.S. graduate students will be trained in his laboratories. The introduction of a new EPR spectrometer (co-funded by the University of Hawaii) will be unique in the state and will greatly enhance the infrastructure of this geographically-remote location. The alkyl-alkyl cross coupling reactions represent high risk / high reward chemistry that may play crucial roles in synthesis of saturated carbon-carbon bonds, important feedstocks for the pharmaceutical and chemical industries.