CAREER: Dynamic Surface Gradients for Studies of Cell Polarization and Cell Migration

化学系(CHE)的分析和表面化学项目以及分子和细胞生物系(MCB)的细胞系统项目将支持北卡罗来纳大学教堂山分校化学系Muhammad N.Yousaf教授的职业发展计划。尤萨夫教授和他的学生将开发一类电活性和动态表面，以研究细胞极性和细胞迁移。微流控和高分辨率活细胞荧光显微镜技术以及遗传编码的生物传感器将被用来产生动态表面梯度，以研究细胞定向迁移过程中的内部信号。这项研究将为研究生和本科生提供多学科培训。尤萨夫教授还将把微流体学和生物相关系统表面表征的研究与教育活动结合起来，重点是与当地一所迎合服务不足的少数群体的大学进行研究和指导活动的交流。

The Analytical and Surface Chemistry Program of the Division of Chemistry (CHE)and the Cellular Systems program of the Division of Molecular and Cell Biology (MCB)will support the CAREER development plan of Prof. Muhammad N. Yousaf of the Department of Chemistry at the University of North Carolina at Chapel Hill. Prof. Yousaf and his students will develop a class of electroactive and dynamic surfaces to study cell polarity and cell migration. Microfluidic and high-resolution live-cell fluorescence microscopy techniques along with genetically encoded biosensors will be used to generate dynamic surface gradients to study internal signaling during directed cell migration. The research will provide multidisciplinary training for graduate and undergraduate students. Prof. Yousaf also will integrate research in microfluidics and surface characterization of biologically relevant systems with educational activities focused on implementing the exchange of research and mentoring activities with a local university that caters to underserved minority groups.