MRI: Acquisition of an FPLC Liquid Chromatography System for Use in Biomolecule Purification, Protein Analysis, and Research Training at Seattle University

该奖项由2009年《美国复苏与再投资法案》(Public Law 111-5)资助。这一重大研究仪器(MRI)奖项用于资助购买快速蛋白质液相色谱(FPLC)生物分子纯化系统，以支持西雅图大学教职员工的跨学科联盟，以及他们在本科生-教员研究、跨部门合作和科学界拓展方面的计划。由FPLC支持的教职员工研究将被转化回课堂，以支持西雅图大学的教育使命。该仪器将为学生提供行业标准纯化系统的研究培训，并为本科生继续攻读研究生或获得生物技术行业的技术职位提供实践经验。来自生物、化学、护理和机械工程系的教员将在广泛的科学研究领域使用FPLC，包括药理学/毒理学、生物化学、微生物学、进化生物学、毒理学和生物工程；所有这些领域都专注于具有生物学意义的基本问题，同时促进未来科学家和专业人员的培训。FPLC的师生研究和技术创新将直接纳入高级课程，所有教师研究项目基本上都是由本科生研究人员进行的。此外，与当地中学科学班建立服务学习伙伴关系将增加学生对生物科学的兴趣和欣赏，并使参与其中的中学生继续进行科学探索。项目成果将通过西雅图大学跨学科生命科学研究实验室网站公布。

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).This Major Research Instrumentation (MRI) award funds the acquisition of a fast protein liquid chromatography (FPLC) biomolecule purification system to support an interdisciplinary consortium of Seattle University faculty, their programs in undergraduate student-faculty research, interdepartmental collaboration, and scientific community outreach. Faculty research enabled by the FPLC will be translated back into the classroom in support of Seattle University's educational mission. The instrument will provide research training to students on the industry-standard purification system and supply practical experience for undergraduates continuing on to graduate school or obtaining technical positions in the biotechnology industry. Faculty members from the Biology, Chemistry, Nursing, and Mechanical Engineering departments will utilize the FPLC across a wide range of scientific research areas including pharmacology/toxicology, biological chemistry, microbiology, evolutionary biology, toxicology, and bioengineering; all of which focus on essential questions of biological significance while promoting the training of future scientists and professionals. Student-faculty research and the technological innovation of the FPLC will be directly incorporated into advanced courses, and all faculty research projects are substantially conducted by undergraduate researchers. Additionally, Service-learning partnerships with local middle school science classes will lead to increased interest and appreciation for the biological sciences, and continued scientific exploration for participating middle school students. Project outcomes will be available through the Seattle University Interdisciplinary Life Sciences Research Lab website.