Acquisition of Upgraded NMR Instrumentation for Chemistry Research, Education and Training

根据化学研究仪器和设施：部门多用户仪器计划（CRIF:MU）的这份合同，加州大学洛杉矶分校（UCLA）的Albert Courey教授和他的同事将获得一台控制台和冷冻探针，以升级一台500 MHz核磁共振光谱仪。将调查的项目包括：(a)富勒烯化学和有机材料，(b)亲电金属中心与芳香族杂环的反应，(c)有机合成和促进分子发现的合成方法的发展，(d)创造非天然分子的新策略，(e)天然产物合成新方法的发展，以及(f)膦催化的新环化反应及其在全合成和组合化学中的应用。核磁共振（NMR）波谱是化学家用来研究分子结构的最有力的工具之一。它用于识别未知物质，跟踪化学反应的进展，表征分子内原子的特定排列，以及研究固体和溶液中分子之间相互作用的动力学。获得最先进的核磁共振光谱仪是必不可少的化学家谁正在开展前沿研究和培养学生在现代研究技术。这些核磁共振研究的结果将对加州大学洛杉矶分校的合成有机化学研究产生影响。该仪器将提供给加州州立大学洛杉矶分校（CSULA）和加州理工学院的用户。

With this award from the Chemistry Research Instrumentation and Facilities: Departmental Multi-User Instrumentation program (CRIF:MU), Professor Albert Courey and colleagues from the University of California at Los Angeles (UCLA) will acquire a console and cryoprobe to upgrade a 500 MHz NMR spectrometer. Projects that will be investigated include: (a) fullerene chemistry and organic materials, (b) reactions of electrophilic metal centers with aromatic heterocycles, (c) organic synthesis and synthetic methods development for the advancement of molecular discovery, (d) new tactics to create non-natural molecules, (e) development of new methods for the synthesis of natural products, and (f) development of new phosphine-catalyzed annulation reactions and their application to total synthesis and combinatorial chemistry.Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to follow the progress of chemical reactions, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solids and in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research and training students in modern research techniques. The results from these NMR studies will have an impact in synthetic organic chemistry research at UCLA. The instrument will be available to users at California State University Los Angeles (CSULA) and Cal Poly.