Collaborative Research: Causes and Consequences of Signal Evolution

Martins LAY提案摘要IOS- 1052247多种性状之间的紧密整合可能受到激素的影响，激素具有广泛的影响。 这种整合相关性状的机制可能会限制性状的进一步进化，限制可能发生的变化。该项目将详细说明如何通过分析相关特征的生理机制来“拉开”相关特征的集合。该项目将研究蜥蜴属中的12个密切相关的物种，其中有一个特定的新特征的重复起源。该项目将研究视觉和化学通讯共同进化的生理和遗传机制，评估信号产生和信号接收所涉及的特征。当研究物种密切相关时，PI还将开发分析相关性状数据所需的统计方法。由此产生的能够进行这种统计分析的软件将在网上免费提供，供其他研究人员使用。有各种更广泛的影响。首先，本科生和研究生将接受培训，他们将与生物化学，分子生物学，神经生理学，动物行为学，进化生物学和生物统计学的研究人员合作。其次，这笔资金将通过在美国不同学科和机构的研究人员之间建立合作来加强研究和教育的基础设施，以及在墨西哥，许多研究物种都在那里。最后，研究所将通过以下方式提高公众对科学和技术的认识：1）与印第安纳州的两家科学博物馆合作，根据受资助的研究建立展览; 2）通过现有的在线数据库服务提供数据（Ethosource）;以及3）将研究成果与PI与当地K建立的持续外展活动联系起来，12名科学教师协助开发与项目所涉及的科学主题相关的教学单元。

Martins LAY ABSTRACT for proposal IOS- 1052247 Tight integration among multiple traits can be influenced by hormones, which have wide-ranging effects. Such mechanisms that integrate sets of correlated traits can potentially constrain further evolution of traits, limiting changes that can occur. The project will detail how sets of correlated traits may be "pulled apart" by analyzing physiological mechanisms underlying suites of correlated characters. The project will study twelve closely related species in a genus of lizards in which there are repeated origins of a specific novel trait. The project will study physiological and genetic mechanisms underlying the coevolution of visual and chemical communication, assessing traits involved in signal production and signal reception. The PIs will also develop statistical methods needed to analyze data on correlated traits when the study species are closely related. The resulting software enabling such statistical analyses will be made freely available online for use by other researchers. There are diverse broader impacts. First, undergraduate and graduate student will be trained and they will collaborate with researchers in biochemistry, molecular biology, neurophysiology, animal behavior, evolutionary biology, and biostatistics. Second, the funding will enhance infrastructure for research and education by establishing collaborations between researchers in different disciplines and institutions within the US, and also in Mexico where many of the study species occur. Finally, the PIs will enhance scientific and technological understanding by the public by 1) collaborating with two Indiana science museums to establish displays based on the funded research; 2) making data available by means of an existing online database service (Ethosource); and 3) connecting research outcomes with ongoing outreach activities that the PIs have established with local K-12 science teachers to assist in developing teaching units related to the science topics involved in the project.