Negative Ion Photoelectron Spectroscopy Studies of Spin-State Dependent Substituent Effects on Aromatic Nitrenes

国家科学基金会化学部的化学结构，动力学和机制计划支持普渡大学的Paul Wenthold教授使用负离子光电子能谱测量氮烯的自旋态能量。 这项研究的两个主要目标是了解自由基稳定部分（如呋喃基和吡啶基-N-氧化物）对基态和激发态能量的作用，以及通过使用角群来研究几何约束对这些测量的影响。这项研究的更广泛影响包括在Wenthold实验室中用于测量高自旋态能量的先进实验设备，为各级科学家提供了一个独特的培训场所。 反应性和结构的气相研究可以影响化学的所有领域，以及材料科学与工程等其他学科，并且芳香族氮烯已被提议在交联实验、光刻中应用，作为感光剂在摄影过程中和光致抗蚀剂技术中。这项工作也有可能影响新的光亲和标记的发展，用于识别参与生物机制的蛋白质的结合位点。 温特霍尔德实验室在培养女科学家方面享有盛誉，他们将利用这笔赠款发起一项新的努力，指导有家庭的研究生，他们在高等教育中面临的特殊挑战往往被忽视。

The Chemical Structure, Dynamics and Mechanisms Program in the Chemistry Division at the National Science Foundation supports Professor Paul Wenthold of Purdue University for the measurement of spin state energies of nitrenes using negative ion photoelectron spectroscopy. The two main goals of this research are to understand the role of radical stabilizing moieties, such as furanyl and pyridinyl-N-oxide, on the ground and excited state energies, and to study the effect of geometrical constraints on these measurements through the use of angular groups.Broader impacts of the research include the advanced experimental apparatus in the Wenthold laboratory for making measurements of high spin state energies, providing a unique training ground for scientists at all levels. Gas-phase studies of reactivity and structure can impact all areas of chemistry, as well as other disciplines such as material science and engineering, and aromatic nitrenes have been proposed to have applications in cross-linking experiments, photolithography, as light-sensitive agents in photographic processes and in photoresist technology. The work also has the potential to impact the development of new photoaffinity labels for identifiying the binding sites of proteins involved in biological mechanisms. The Wenthold laboratory has a strong reputation for training female scientists, and they will launch a new effort with this grant to mentor graduate students with families, whose particular challenges in higher education are often overlooked.