The photonic immunochip: retrieving individual Enzyme-linked Immuno Sorbent Assay (ELISA) array-units using optical waveguide multicolour fluorescence

提高体外免疫诊断试验的灵敏度和可用性是开发实时有效的工具来检测传染病、癌症、过敏和自身免疫性疾病的关键目标。其目的是通过减少背景噪音来提高这些检测的灵敏度，背景噪音一直是常用的ELISA技术的一个特征。这将通过开发一种新型的光学集成波导阵列来实现，该阵列支持大范围的分布式测试，包括基于新的多色检测方案的一些测试。这种大规模并行的方法将为新一代低成本、高效率的诊断测试奠定基础。

Improving the sensitivity and availability of in-vitro immuno-diagnostic tests is a critical goal towards developing real time efficient tools for the detection of infectious diseases, cancers, allergies and auto-immune diseases. The goal is to increase the sensitivity of these tests by reducing background noise that has been a feature of the commonly used ELISA technology. This will be achieved by developing a novel optical integrated waveguide array supporting a large range of distributed tests, including several based on a novel multi-colour detection scheme. This massively parallel approach will underpin a new generation of low-cost, efficient diagnostic tests.