CAREER: Molecular Reorganization of Simple Substrates into Complex Products

有了这个职业奖，化学合成项目支持德克萨斯大学西南医学中心的utttam K. Tambar教授的研究。Tambar教授将开发新的分子重组过程，其中简单的起始材料选择性地重新排列成更复杂和更有价值的产品。几十年来，分子重排一直在有机化学中盛行。事实上，化学反应的一些最基本的原理是在分子重排的背景下阐明的。Tambar教授对研究不发达的分子重组领域很感兴趣。他的团队将开发选择性重排，以促进复杂分子的合成，包括多环天然产物。在开发这些新转化的过程中，Tambar教授的团队将重点阐明化学反应性的新概念。Tambar教授还将发起新的教育活动，将他的研究目标与他的承诺结合起来，教育更广泛的化学社区在提高我们的生活质量方面的作用。这些倡议包括向小学生介绍化学合成，改善他所在大学的研究生和博士后科学家的化学安全培训，以及为达拉斯-沃斯堡地区的公众组织科学卡姆斯。

With this CAREER award, the Chemistry Synthesis program is supporting the research of Professor Uttam K. Tambar of the University of Texas Southwestern Medical Center. Professor Tambar will develop novel molecular reorganization processes, wherein a simple starting material selectively rearranges into a more complex and more valuable product. Molecular rearrangements have pervaded organic chemistry for decades. In fact, some of the most fundamental principles of chemical reactivity were elucidated in the context of molecular rearrangements. Professor Tambar is interested in studying areas of molecular reorganization that are underdeveloped. His group will develop selective rearrangements that will facilitate the synthesis of complex molecules, including polycyclic natural products. In the process of developing these new transformations, Professor Tambar's group will focus on elucidating new concepts in chemical reactivity.Professor Tambar will also initiate new educational activities that will integrate his research goals with his commitment to educate the broader community of chemistry's role in improving our quality of life. These initiatives include introducing elementary school students to chemical synthesis, improving Chemical Safety Training for graduate students and postdoctoral scientists at his university, and organizing Science Cafés for the general public of Dallas-Fort Worth area.