Novel polymeric microparticles for slow-release intrathecal delivery of analgesics

未缓解的慢性疼痛是一个未满足的医疗需求的大领域，对全世界数百万人的生活产生了不利影响。该项目旨在开发创新方法，将一种新型止痛药物输送到脊髓液中，靠近将疼痛信息传递到大脑的细胞。 我们的目标是开发一种新的治疗方法，以延长那些无法从现有止痛药中获益的患者的疼痛缓解时间。 即将开发的技术有可能应用于广泛的镇痛药物治疗。

Unrelieved chronic pain is a large area of unmet medical need, adversely affecting the lives of millions of people worldwide. This project seeks to develop innovative methods for delivering a novel pain-relieving medication into the spinal fluid in close proximity to the cells that transmit pain messages to the brain. The goal is to develop a new treatment to produce prolonged periods of pain relief in those patients who do not obtain benefit from existing pain medications. The technology that will be developed has the potential to be applied to a broad range of analgesic drug treatments.