CAREER: Hydrazone-Based Switches - Simple Systems for Sophisticated Functions

在这个由化学系高分子、超分子和纳米化学计划资助的项目中，达特茅斯学院的Ivan Aprahamian博士开发了易于制造、模块化和可调的基于肼的开关，并研究了将它们集成到聚合物和液晶中的方法。这一建议为开发自适应功能材料(如化学激活的执行器、传感器和分子机器)提供了一种新的战略，通过使用合成的直接构建块来实现。预计这种方法将有助于系统的结构-性质分析，从而能够快速生产i)用于纳米技术应用的分子机器，ii)可将化学能转换为机械运动的刺激响应性聚合物，以及iii)可用作环境污染物传感器的pH敏感液晶。这项研究的更广泛影响包括：i)利用ACS SEED项目和其他努力留住不同水平的学生(高中生、本科生和研究生)，ii)试验和评估可以增强学生学习经验的课堂技术，以及iii)开发动手自组装演示，以教育公众与超分子化学和纳米技术相关的重要概念。

In this project funded by the Macromolecular, Supramolecular and Nanochemistry Program of the Chemistry Division, Dr. Ivan Aprahamian of Dartmouth College develops easy to make, modular and tunable hydrazone-based switches, and studies ways to integrate them into polymers and liquid crystals. This proposal offers a new strategy for the development of adaptive functional materials (such as chemically activated actuators, sensors and molecular machines) by using synthetically straightforward building blocks. It is expected that this approach will facilitate the structure-property analysis of the systems, which will enable the rapid production of i) molecular machines for nanotechnology applications, ii) stimuli-responsive polymers that can convert chemical energy into mechanical motion, and iii) pH sensitive liquid crystals that can be used as sensors for environmental pollutants. The broader impacts of this research entail i) using the ACS SEED project and other endeavors to retain students of different levels (high school, undergraduate and graduate students) in the sciences, ii) piloting and assessing classroom technologies that can augment the learning experience of students, and iii) developing hands-on self-assembly demonstrations to educate the general public about important concepts related to supramolecular chemistry and nanotechnology.