SusChEM: RUI: Accessing Reactive, Unsaturated Co(I) Fragments for Stoichiometric and Catalytic C-H Bond Activation/Functionalization

来自国家科学基金会化学部化学催化计划的支持将使圣玛丽山大学的克里斯托弗布拉德利教授能够研究三价（Cp）钴（I）源介导化学计量和催化碳-氢键活化的能力。计算和合成研究的结合将允许在单体和聚集体[Cp-Co]片段中建立C-H活化的结构/反应性趋势。具体而言，将以催化烷烃脱氢为目标。拟议的研究涉及在研究环境中继续指导高中和本科生。特别是，在马里兰州和华盛顿大都会地区的经济困难的高中学生将有机会进行合成化学的夏季研究。通过第三个世纪学者计划，将鼓励学生们继续在圣玛丽玛丽接受大学教育。脂肪烃转化为不饱和产物对包括商品化学品和聚合物合成在内的一系列领域具有重要价值。因此，使用更丰富的金属作为催化剂在温和的条件下进行这种转化是理想的。该奖项支持的高中生和本科生所培养的能力将为他们攻读化学科学高级学位做好准备。

Support from the Chemical Catalysis Program of the Chemistry Division of the National Science Foundation will allow Professor Christopher Bradley of Mount St. Mary's University to investigate the ability of cyclopentadienyl (Cp) cobalt(I) sources to mediate stoichiometric and catalytic carbon-hydrogen bond activation. A combination of computational and synthetic studies will permit structure/reactivity trends to be established for C-H activation in both monomeric and aggregate [Cp-Co] fragments. Specifically, catalytic alkane dehydrogenation will be targeted. The proposed research involves continued mentoring of both high school and undergraduate students in a research environment. In particular, economically disadvantaged high school students in the Maryland and Washington D.C. metro area will have the opportunity to conduct summer research in synthetic chemistry. The students will be encouraged to continue their college education at Mount St. Mary's, through the Third Century Scholar Program.The conversion of aliphatic hydrocarbons to unsaturated products has great value to a range of fields, including commodity chemical and polymer synthesis. Performing this transformation using more abundant metals as catalysts under milder conditions would therefore be ideal. The abilities developed by both high school and undergraduate students supported by this award will prepare them well for pursuit of advanced degrees in the chemical sciences.