Microscale Comprehensive Two-Dimensional Gas Chromatography

本研究的最终目标是创建一个低资源，全面的二维气相色谱微系统原型，完全由硅微加工组件组成，使用现有的，概念验证的2级微制造热调制器。知识优势：全面的二维气相色谱法可以说是已知的分离和检测极其复杂的S/VOCs混合物组分的最有效方法。更广泛的影响：成功的项目将扩展最先进的小型、廉价、交钥匙仪器，用于识别/定量复杂混合物中的有机化合物。这是先前涉及来自机械/电气工程、化学、应用物理和环境健康科学的学生/教师的合作工作的自然延伸，这将促进微系统集成、分离科学和公共卫生领域的跨学科指导/学习。

The ultimate goal of this research is to create a low-resource, comprehensive two-dimensional gas chromatographic microsystem prototype comprised entirely of Si-micromachined components that uses an extant, proof-of-concept, 2-stage microfabricated thermal modulator.Intellectual Merit: Comprehensive two-dimensional gas chromatography is arguably the most effective method known for separating and detecting the components of extremely complex mixtures of S/VOCs. Broader Impacts: The successful project will extend the state-of-the-art in small, inexpensive, turn-key instrumentation for identifying/quantifying organic compounds in complex mixtures. This is a natural extension of previous collaborative work involving students/faculty from mechanical/electrical engineering, chemistry, applied physics, and environmental health sciences, which will promote interdisciplinary mentoring/learning in microsystem integration, separation science, and public health.