MRI: Acquisition of a Dionex Accelerated Solvent Extractor for Biogeochemistry, Toxicology, and Marine Science Research at Hawaii Pacific University

这笔资金用于购买Dionex加速溶剂萃取（ASE）系统，以增加教师和学生的研究机会，并改善HPU的教学基础设施。ASE系统将用于由NSF和其他机构资助的各种活跃研究项目中，这些项目需要经常使用ASE设备提取脂质、环境污染物和天然代谢产物。该仪器将用于许多不同的项目，包括(a)从西北太平洋深埋的Shimokita煤层（海底以下1498.48米和2406.84米）分离的嗜压细菌进行脂质生物合成的碳同位素分选；(b)评估Kawai 'nui沼泽生态系统的历史变化；(c)测量野生海豚的应激诱导激素，作为环境对海豚种群负面影响的指标(d)天然产物化学文库的开发；(e)测量海洋脊椎动物组织中的有机污染物。HPU目前正在从以本科生为主的非博士转变为将教学机构授权为具有强大研究计划的综合性大学，这些最先进的仪器将有助于促进这种转变。博士后研究员、硕士研究生和本科生将接受仪器使用方面的培训。夏威夷太平洋大学（HPU）是瓦胡岛的一所少数民族本科研究机构，与美国大陆相比，夏威夷的高等教育中心很少。HPU的学生人数包括当地夏威夷原住民和太平洋岛民，他们来夏威夷接受大学教育。因此，该仪器的资助将对生物学、生物化学、海洋生物学和海洋学等领域的研究和教育的不同学生群体产生广泛的影响。

This award funds the acquisition of a Dionex Accelerated Solvent Extraction (ASE) system to enhance faculty and student research opportunities and to improve teaching infrastructure at HPU. The ASE system will be used in a variety of active research projects funded by NSF and other agencies which require frequent use of ASE equipment for extraction of lipids, environmental contaminants, and natural metabolic products. The instrument will be used for a number of diverse projects including (a) carbon isotope fractionation in lipid biosynthesis by piezophilic bacteria isolated from the deeply buried Shimokita Coalbed (1498.48 and 2406.84 meter below the seafloor) in the northwest Pacific; (b) assessing historical changes in Kawai`nui marsh ecosystem; (c) measuring stress-induced hormones in wild dolphins as an indicator of negative environmental impacts on dolphin populations (d) the development of natural product chemical libraries; and (e) measuring organic contaminants in tissues of marine vertebrates. HPU is currently in transition from a predominantly undergraduate, non-Ph.D. granting teaching institution into a comprehensive university with a strong research program, and such state-of-the-art instrumentation will help facilitate this transition. Postdoctoral research associates and M.S. graduate and undergraduate students will be trained on the use of the instrument. Hawaii Pacific University (HPU) is a minority serving undergraduate research institution on the Island of Oahu in a state with few centers of higher learning in Hawaii compared with the continental United States. The HPU student population includes significant representation by local native Hawaiians as well as Pacific Islanders that come to Hawaii for a college education. Hence the funding of this instrumentation will have broad impacts on a diverse student population in research and education in fields such as Biology, Biochemistry, Marine Biology and Oceanography.