MRI: Acquisition of a Multiwavelength Raman Spectroscopy Facility for Catalysis, Biological, Nanoscale and Materials Research

在主要研究仪器(MRI)计划的这一奖项和化学研究仪器(CRIF)计划的支持下，罗切斯特大学的迈克尔·内迪格教授和他的合作者将获得一台多波长拉曼光谱仪，该光谱仪围绕具有多条激光线路的三重光谱仪构建，可以收集从近红外到近紫外区的拉曼数据。该区域的拉曼光谱用于测量材料的振动频率。它提供了有关物质的化学成分和结构的信息。它是一种广泛使用的工具，用于了解化学和生物系统的性质，并在材料研究中使用。该仪器将是一个多用户设施，向大学和罗切斯特地区的用户开放，包括圣约翰·费舍尔学院和纽约州立大学杰内索分校的教职员工。它将促进各级学生在研究和课程工作方面的培训。该奖旨在加强各级的研究和教育，特别是在下列领域：(A)研究非贵金属催化有机合成的结构、键和机理；(B)开展飞秒受激拉曼光谱探测的超快光化学；(C)在细胞和组织水平上分析生物标本；(D)研究血红素蛋白和改良金属蛋白中的第二球效应以进行能量转换；(E)分析合成处方；(F)阐明A-β多肽在金纳米胶体上的结合构象；以及(G)研究用于活细胞基因输送的中空微针。

With this award from the Major Research Instrumentation (MRI)program and support from the Chemistry Research Instrumentation (CRIF) program, Professor Michael Neidig and collaborators from the University of Rochester will acquire a multiwavelength Raman spectrometer built around a triple spectrometer with multiple laser lines to allow collection of Raman data from the near-IR to near-UV regions. Raman spectroscopy in this region is used to measure the vibrational frequencies of a material. This provides information on the chemical composition and structure of substances. It is a widely used tool to understand the properties of chemical and biological systems and in materials research. The instrument will be a multi-user facility open to users at the university and in the Rochester area including faculty at St. John Fisher College and SUNY-Geneseo. It will advance the training of students in their research and course work at all levels. The award is aimed at enhancing research and education at all levels, especially in areas such as (a) investigating structure, bonding and mechanism in non-precious metal catalysis for organic syntheses; (b) carrying out ultrafast photochemistry probed by femtosecond stimulated Raman spectroscopy; (c) analyzing biological specimens at the cell and tissue level; (d) studying second-sphere effects in heme proteins and engineered metalloproteins for energy conversion; (e) analyzing compounded prescriptions; (f) elucidating binding conformation of A-beta peptides over gold nanocolloids; and (g) studying hollow microneedles for gene delivery in living cells.