Nanoparticle reinforced bioactive polysaccharide hybrid composites for medical applications (Nanobiocomp)

多糖的纳米颗粒增强可以提供一种通用的工具来设计和制造新一代的生物活性植入物和人工组织基质材料，其中优异的生物力学稳定性可以与柔性纤维支架结构的高弹性相结合。建议的项目涉及两个主要问题：i.纳米生物活性陶瓷粉末（TiO 2和Cas（PO 4）3/OH）在再生多糖基质中的分散以及生物活性织物和多层梯度结构的制造ii.）机械性能和生物功能效率的表征。埃尔兰根大学将处理粉末/多糖混合复合材料的加工和支架结构的制造。成光大学将与医学院合作，分析纳米颗粒增强混合材料复合材料和结构的机械和生物行为。

Nanoparticle reinforcement of polysaccharides may provide a versatile tool to design and manufacture a novel generation of bioactive implant and artifical tissue matrix materials where an excellent biomechanical stability might be combined with high elasticity of flexible fibrous scaffold structures. The proposed project involves two major issues: i.) dispersion of the nanosized bioactive ceramic powder (TiCh and Cas(PO4)3/OH) in regenerated polysaccharide matrix and fabrication of bioactive textile and multilayer gradient structures ii.) characterization of mechanical behavior and biofunctional efficency. Processing of powder/ polysaccharide hybrid composites and fabrication of scaffold structures will be dealt with at Erlangen University. At Sung Kwon Kwan University the nanoparticle reinforced hybrid material composites and structures will be analysed for the mechanical and biological behavior in cooperation with the medical school.