Phase Separation of Reactive Oxygen with Multi-compartmented Sensitizers

化学结构、动力学和机制项目支持纽约城市大学布鲁克林学院亚历山大·格里尔教授的基础研究。格里尔教授将开发准确研究活性氧（ROS）化学的技术。单线态氧和烷氧基自由基等ROS在机械化学和合成化学中具有广泛的重要性，对理解生物学中的氧化过程至关重要。本研究旨在创造改性聚合物表面，为空间控制ROS的产生和传递提供基质。新合成的聚合物将用于研究有机溶液中的受控光氧化化学，但也可能在细菌灭活系统中具有更广泛的科学影响。该项目将支持对研究生的培训，使他们掌握必要的光科学方法。格里尔教授和他的学生将在当地的高中和大学开展推广活动，强调改善太阳能资源和水净化研究的价值。这些会谈将在联合国IYL2015（国际光与光基技术年）的背景下进行。有了这个奖项，新的非均相方法将被开发出来，用于物理隔离敏化剂和过氧化物分子，以在聚合物表面产生单线态氧和烷氧基自由基。该研究将提供一种进行可控氧化化学的方法，这将促进未来在选择性氧化、化学老化、流动和消毒化学方面的一系列研究。这种非均相化学的一个关键特征是能够打破表面结合的过氧化物键，以调节形成的烷氧基自由基。这项研究将与有机化学相关，并可能对材料的氧化降解产生更广泛的影响。

The Chemical Structure, Dynamics and Mechanisms program is supporting fundamental research by Professor Alexander Greer at the City University of New York, Brooklyn College. Professor Greer will develop techniques for accurately studying the chemistry of reactive oxygen species (ROS). ROS such as singlet oxygen and alkoxy radicals are of broad importance in mechanistic and synthetic chemistry and critical to understanding oxidative processes in biology. This research seeks to create modified polymer surfaces which will provide a matrix for spatially controlled generation and delivery of ROS. Newly synthesized polymers will be used to study controlled photooxidation chemistry in organic solutions, but also may have broader scientific impact in bacterial inactivation systems. The project will support training of research students to ground them in the necessary photoscientific methods. Professor Greer and his students will engage in outreach to local high schools and colleges, emphasizing the value of improving solar energy resources and water purification research. These talks will be presented in the context of the United Nations IYL2015 (International Year of Light and Light-Based Technologies). With this award, new heterogeneous methods will be developed for the physical isolation of sensitizer and peroxide molecules to generate singlet oxygen and alkoxy radicals at polymer surfaces. The research will provide a method for conducting controlled oxidation chemistry that will facilitate a range of future studies on selective oxidation, chemical aging, flow and disinfection chemistry. One key feature of this heterogeneous chemistry will be the ability to break surface-bound peroxide bonds to regulate the alkoxy radicals formed. The research will be relevant to organic chemistry, and has potentially broader implications related to the oxidative degradation of materials.