An Interdisciplinary Faculty Community Using a Protein-focused Course Based Undergraduate Research Experience (CURE) to Improve Student Learning

《本科生物学报告的愿景和变化》以及其他出版物建议将核心概念和技能整合到整个课程中，并关注以学生为中心的学习环境，使用经过验证的高影响力实践，例如为所有学生提供研究经验。该项目将利用基于课程的本科研究体验（CURE），让学生参与到本科研究中，并将研究活动融入课堂。总体目标是创建一个以蛋白质为中心的CURE的教师网络，为生物化学家、化学家和生物学家社区服务，并研究CURE的基本方面，以改善教学发展。通过将定量的、真实的研究纳入课堂和课程，该项目有可能改变参与机构教学实验室的影响。该项目汇集了来自两年制和四年制（本科和研究密集型土地赠款）机构的STEM学科教师，通过创建专注于苹果酸脱氢酶的自我支持和可持续的以蛋白质为中心的CUREs来填补CUREs的空白。这个以蛋白质为中心的治愈社区将研究治愈的两个关键方面：1)治愈的长度（课程长治愈（cCUREs）或较短的模块化治愈（mCUREs））的影响，以及2)跨课程或机构的研究合作的作用，以评估它们对学生学习，保留和动机的重要性。学生和教师的成果将使用经过验证的评估工具进行评估，并由外部评估人员与内部咨询团队和外部咨询委员会以及参与者一起工作。该项目将建立一个框架，支持一个持续的、以蛋白质为中心的CURE社区，以促进高等教育机构采用该社区，从而影响大量不同的学生。

The Vision and Change in Undergraduate Biology Report, as well as other publications, recommend integration of core concepts and skills throughout the curriculum and a focus on student-centered learning environments using validated high impact practices, such as research experiences for all students. This project will engage students in undergraduate research and incorporate research activities into a classroom context using a Course-based Undergraduate Research Experience (CURE). The overall goal is to create a faculty network using protein-centric CUREs to serve a community of biochemists, chemists and biologists, and also examine essential CURE aspects to improve pedagogical development. This project has the potential to transform the impact of teaching laboratories at participating institutions by the incorporation of quantitative, authentic research into the classroom and curriculum. This project brings together STEM disciplinary faculty from two and four year (undergrad and research intensive-land grant) institutions to fill a CUREs gap by creating self-supporting and sustainable protein-centric CUREs focused on the enzyme malate dehydrogenase. This protein-centric CUREs community will examine two critical aspects of a CURE: 1) the impact of the length of CUREs (course long CUREs (cCUREs) or shorter modular CUREs (mCUREs)), and 2) the role of research collaborations across courses or institutions to assess their importance for student learning, retention and motivation. Student and Faculty outcomes will be assessed using validated assessment tools and an outside evaluator working with both an internal advisory team and an external advisory board as well as the participants. This project will build a framework supporting a sustained, protein-centric CURE community to foster adoption amongst higher education institutions to impact a large and diverse set of students.