Vitamin D regulation of the skin innate immune response (B13)

免疫细胞的协同反应是通过促进适当的炎症和抗菌宿主反应来确保组织内环境稳定的关键。在这个项目中，我们将分析皮肤中先天免疫细胞在炎症和抗菌宿主对细胞内病原体的反应过程中的协作。特别是，我们想了解维生素D激素在调节这些相互作用中的作用。从长远来看，这类研究可能对设计新的宿主导向疗法具有重要意义。

The cooperative response of immune cells is crucial to ensure tissue homeostasis by promoting an appropriate inflammatory and antimicrobial host response. In this project we will analyse the collaboration of innate immune cells in the skin during the inflammatory and antimicrobial host response against intracellular pathogens. In particular, we want to understand the role of vitamin D hormone in regulating these interactions. In the long term such studies could be of importance for the design of novel host-directed therapies.