Plasma-synthesized magnetic nanoparticles arrested in radiation-optimized hydrogels: towards a biodegradable medical actuator (PARTACT).

杂化水凝胶/磁性纳米颗粒复合材料在适当的外加磁场下表现出较大的可逆形状变化。结合软物质和硬物质的特性，这些新的“智能”材料在生物医学科学的大量应用中显示出巨大的前景，如细胞拉伸或刺激组织再生。在资助期1和2分别证明了各组成部分的合成和基本功能之后，在生物医学领域的应用将是本提案的中心。这包括构建生物致动器以及药物释放系统，这将在再生医学领域有用。

Hybrid hydrogel/magnetic nanoparticle composites exhibit large reversible shape changes when exposed to appropriate external magnetic fields. Combining properties of soft and hard matter, these new "smart" materials show great promise for a plethora of applications in biomedical sciences, like cell stretching or stimulated tissue regeneration. After synthesis of the components and basic function has been demonstrated in funding periods 1 and 2, respectively, application within the area of biomedicine will be in the center of the present proposal. This includes construction of bioactuators as well as a drug release system, that will be useful in the area of regenerative medicine.