MRI: Acquisition of A 90 MHz NMR Spectrometer: Initiating a Bioinspired Undergraduate Student Achievers in Research (USTAR) Program in a Two-Year College

该奖项由主要研究仪器和化学仪器项目支持。密苏里州立大学西平原分校的Joseph Rugutt教授和他的同事们正在购买一台90兆赫的核磁共振（NMR）光谱仪。一般来说，核磁共振波谱是化学家用来检查分子结构的最有力的工具之一。它用于识别未知物质，表征分子内原子的特定排列，以及研究溶液或固体状态下分子之间相互作用的速率。核磁共振的研究提高了对合成有机/无机化学，材料化学和生物化学的理解。该仪器是本科学生教学和研究中不可或缺的一部分，影响绿色化学和用于加速反应速率的可回收离子液体。许多学生在一个名为“本科生研究成就者”（USTAR）的生物启发计划中使用光谱仪，该计划促进学生在该机构和密苏里州邻近高中参与STEM（科学技术、工程和数学）。核磁共振光谱仪的奖励旨在加强各级的研究和教育。这种仪器的获取尤其影响了合成的生物测定导向查尔酮的表征，查尔酮是形成重要生物化合物的核心的芳香酮。合成的纳米材料可用于绿色化学和分子建模以及光谱学研究。研究人员正在生成一个查尔酮的小库，用来测试其对生物目标的影响。他们也在研究离子液体作为催化剂来加速化学反应。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

This award is supported by the Major Research Instrumentation and the Chemistry Instrumentation Programs. Professor Joseph Rugutt from Missouri State University - West Plains and colleagues are acquiring a 90 MHz nuclear magnetic resonance (NMR) spectrometer. In general, NMR spectroscopy is one of the most powerful tools available to chemists for the examination of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the rates of interactions between molecules in solution or in the solid state. The NMR studies improve understanding of synthetic organic/inorganic chemistry, materials chemistry and biochemistry. This instrument is an integral part of teaching as well as research performed by undergraduate students that impacts green chemistry and recyclable ionic liquids used to accelerate reaction rates. Many students use the spectrometer in a bioinspired initiative named "Undergraduate STudent Achievers in Research" (USTAR) that promotes student participation in STEM (science technology, engineering and mathematics) at the institution and at neighboring high schools in Missouri.The award of the NMR spectrometer is aimed at enhancing research and education at all levels. This instrument acquisition especially impacts the characterization of synthesized bioassay-directed chalcones which are aromatic ketones that form the central core of important biological compounds. The syntheses incorporate nanomaterials that can be used in green chemistry and molecular modeling and for spectroscopic studies. The researchers are generating a small library of chalcones that are tested against biological targets. They are also studying ionic liquids to be used as catalysts to accelerate chemical reactions.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.