Transcriptional addressing of dendritic cells (DCs) with the help of an hPFscn1 derived promotor using DC-addressing polymers for tumortherapy (B05)
Transcriptional addressing of dendritic cells (DCs) with the help of an hPFscn1 derived promotor using DC-addressing polymers for tumortherapy (B05)
批准号:
239229559
负责人:
金额:
$0.0万
依托单位:
依托单位国家:
德国
项目类别:
Collaborative Research Centres
财政年份:
2013
资助国家:
德国
项目状态:
已结题
起止时间:
2012-12-31 至 2020-12-31
中文摘要
该项目将开发dna疫苗,这种疫苗受筋膜蛋白启动子的翻译控制,因此只在树突状细胞中起作用。由于树突状细胞——非分裂细胞——很难转染,E. Wagner和R. Zentel的专业知识将结合开发新的,更有效的刺激反应转染系统,从嵌段共聚物和阳离子低聚物。
英文摘要
This project will develop DNA-vaccines, which are under the translational control of the Fascin-promotor and thus only active in dendritic cells. Since dendritic cells as – non-dividing cells – are rather difficult to transfect, the expertise of E. Wagner and R. Zentel will be combined to develop new, more efficient stimulus responsive transfection systems from blockcopolymers and cationic oligomers.
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专著(0)
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会议论文
国内基金
海外基金
Supply Chain Collaboration in addressing Grand Challenges: Socio-Technical Perspective
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批准号:--
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项目类别:外国青年学者研究基金项目
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批准年份:2024
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负责人:Lim Jia Jia
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依托单位: