3rd International Conference on CRISPR Technologies

第三届CRISPR技术国际会议将于2019年9月16日至18日在德国维尔茨堡举行。本次会议为生物学家、化学家、工程师和伦理学家提供了一个多学科论坛，以推进集群规则间隔短回文重复序列（CRISPR）基因操作技术。在美国化学工程师学会（AIChE）内的一个技术团体——生物工程学会（SBE）的主持下，这次国际会议将汇集知名专家、知名研究人员、年轻研究人员、私营部门的科学家和工程师以及研究生。该小组将评估CRISPR技术的现状，并确定将基因组工程方法整合到细胞、植物和动物中的挑战。重要的是，crispr技术的社会、伦理和经济影响将被着重强调。CRISPR技术在过去十年中发展迅速，并已被证明是基因组工程的变革。CRISPR技术目前和未来的应用范围从药物治疗和器官移植到牲畜、作物、食品生物和工业微生物。虽然我们对不同CRISPR系统的了解正在迅速发展，但生物学家和工程师之间缺乏整合，损害了基础研究在临床和工业应用中的安全有效实施。例如，将生物学家和工程师结合在一起的综合方法将极大地有利于从工程细胞中产生经过crispr编辑的类器官，最终重建可移植到患者体内的组织。此外，基于crispr的方法对于能够在快速变化的气候中更好地发挥作用的牲畜和农业工程至关重要。这些雄心勃勃的目标需要来自多个学科的观点、知识和技术的交叉，而这次会议将为这种合作提供一种机制。此外，基因组编辑更广泛的社会和伦理影响将是一个突出的讨论话题。生物工程学会在组织重要的新科学会议方面有着非常好的记录，会议记录将在AIChE的网站上向公众发布。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

The 3rd International Conference on CRISPR Technologies will be held in Wurzburg, Germany on September 16-18, 2019. This conference provides a multidisciplinary forum for biologists, chemists, engineers, and ethicists to advance Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) technologies for genetic manipulation. Organized under the auspices of the Society for Biological Engineering (SBE), a technical community within the American Institute of Chemical Engineers (AIChE), this international conference will bring together renowned experts, established researchers, young investigators, private sector scientists and engineers, and graduate students. This group will assess the state of CRISPR technologies and identify the challenges of integrating genome engineering approaches in cells, plants, and animals. Importantly, the social, ethical, and economic implications of CRISPR-based technologies will be heavily emphasized. CRISPR technologies have advanced rapidly in the past decade and have already proven to be transformational for genome engineering. Present and future applications of CRISPR technologies range from medicinal therapeutics and organ transplantation to uses in livestock, crops, food organisms, and industrial microbes. While our knowledge of different CRISPR systems is rapidly advancing, the lack of integration between biologists and engineers impairs the safe and effective implementation of basic research into clinical and industrial applications. For example, an integrated approach that brings biologists and engineers together would greatly benefit efforts to produce CRISPR-edited organoids from engineered cells to ultimately reconstruct tissues that could be transplanted into patients. Additionally, CRISPR-based approaches will be critical in engineering livestock and agriculture that can better perform in our rapidly changing climate. These ambitious goals require the intersection of viewpoints, knowledge, and technologies from multiple disciplines, and this conference will provide a mechanism for such collaborations. Furthermore, the broader social and ethical implications of genome editing will be a highlighted topic of discussion. The Society for Biological Engineering has a very strong track record in organizing important new scientific meetings, and the proceedings of the conference will be disseminated to the public on AIChE's website.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.