IUCRC: Planning Grant: Georgia Institute of Technology: Center For Building Reliable Advances and Innovation in Neurotechnology (BRAIN)

在美国，脑部疾病是导致残疾的主要原因。迫切需要新技术来解决这个问题。然而，创造这项技术需要具有独特技术专长的学术研究人员和具有深厚产品开发专业知识的行业公司之间的合作努力。佐治亚理工学院建立可靠的神经技术进步和创新（BRAIN）中心的网站将开发产品就绪的技术创新，以预防大脑疾病，并为受影响的患者提供更好的诊断和治疗。佐治亚理工学院网站还将启动新的以行业为重点的项目，促进多样性和教育。构建上述技术需要对大脑有基本的了解，这受到基础科学和工程技术的限制。理解是通过创新研究推进的；然而，研究的影响目前是有限的，因为创新远远超过了产品化，这是由于在转化管道中的“死亡之谷”中缺乏对创新的引导。为了解决这一缺点，佐治亚理工学院大脑中心网站将通过跨越科学、技术、工程和数学（STEM）领域、模型系统（例如，人类、动物、体外和计算）、空间尺度（例如，神经元到生物体）和脑功能垂直（例如，神经血管和神经系统）来开发产品就绪的神经技术创新。佐治亚理工学院网站的另一个重点领域是神经伦理学。新兴的神经技术带来了与自主性、身份和隐私相关的巨大伦理影响。我们认为，将神经伦理学整合到BRAIN中心的活动中，对于最大化神经技术创新的社会效益、接受度、信任和正义等更广泛的影响至关重要。佐治亚理工学院网站的另一个更广泛的影响将是解决STEM领域代表性不足的问题。佐治亚理工学院位于黑人人口占多数的亚特兰大，它有一个独特的机会，可以通过创业和实习来实现这一目标。从拟议的规划拨款中产生的数据产品可能包括实验、计算、基于文本和/或课程数据。所有数字数据产品的存储将符合《健康保险流通与责任法案》（HIPAA）、《健康信息技术促进经济和临床健康法》以及最终的HIPAA综合规则。此外，这些产品只能通过用户特定的密码保护访问来访问。所有存档资料的保存期限为五年。已经在http://sites.gatech.edu/avl/iucrc.This上创建了一个导航到存档数据的登陆页面，该页面反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

Disorders of the brain are the leading cause of disability in the United States. There is a critical need for new technology to address this problem. However, creating the technology calls for very collaborative efforts between academic researchers with unique technical expertise and industry companies with deep product development expertise. The Georgia Tech site of the Building Reliable Advances and Innovations in Neurotechnology (BRAIN) Center will develop product-ready technology innovations that prevent brain disorders and provide better diagnosis and treatment for affected patients. The Georgia Tech site will also initiate new industry-focused programs promoting diversity and education.Building the aforementioned technologies requires fundamental understanding of the brain, which is limited by the state-of-the-art in basic science and engineering. Understanding is advancing through innovative research; however, research impact is currently limited because innovation greatly outpaces productization due to insufficient shepherding of innovation through the “valley of death” in the translational pipeline. To address this shortcoming, the Georgia Tech BRAIN Center site will develop product-ready neurotechnology innovations by spanning science, technology, engineering, and math (STEM) fields, model systems (e.g., human, animal, in vitro, and computational), spatial scales (i.e., neuron to organism), and brain function verticals (e.g., neurovascular and neurological).Another thrust area of the Georgia Tech site is Neuroethics. Emerging neurotechnologies present enormous ethical implications relating to autonomy, identity, and privacy. We assert that the integration of neuroethics into BRAIN Center activities is critical to maximizing broader impacts such as social benefit, acceptance, trust, and justice in neurotechnology innovation. Another broader impact of the Georgia Tech site will be combatting underrepresentation in STEM fields. Located in Atlanta, which is home to a majority Black population, Georgia Tech has a unique opportunity to leverage its place toward this end through the vehicles of entrepreneurship and internships.Data products to result from the proposed planning grant may include experimental, computational, text-based, and/or curricular data. All digital data products will be stored in compliance with the Health Insurance Portability and Accountability Act (HIPAA), the Health Information Technology for Economic and Clinical Health Act, and the final HIPAA Omnibus rule. Further, these products will be accessible only through user-specific password-protected access. All archived materials will be retained for a period of five years. A landing page for navigation to archived data has already been created at http://sites.gatech.edu/avl/iucrc.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.