MRI: Acquisition of an ABI 3500xL Genetic Analyzer for the WVU Genomics Core Facility

西弗吉尼亚大学（WVU）获得了一份合同，将用ABI 3500xL取代和升级现有的应用生物系统公司（Applied Biosystems）的3130xL基因分析仪，从而增强WVU基因组学和生物信息学核心设施（WVU- gbcf）目前提供的服务。具体来说，这种替代将改善周转时间，产生更高质量的产出，并创造多路复用的能力，所有这些都将加强正在进行的地方和区域研究和教学工作。作为西弗吉尼亚州的土地授予机构，WVU和WVU- gbcf致力于在大学和全州范围内提供培训和支持。WVU- gbcf对通用基因组学相关的研究和课程有浓厚的兴趣，因此，WVU- gbcf为所有WVU校区和大阿巴拉契亚地区的学生提供了许多尖端的实践教育和培训机会。具体来说，该设施为学生和教师提供培训，故障排除和服务，其中DNA测序和/或片段分析是作为本科实验室课程的一部分进行的。此外，WVU-GBCF提供的能力和资源对许多本科生和研究生的论文和论文项目至关重要，从农学上重要的作物植物对气候变化的基因组反应到阿片类药物和精神兴奋剂滥用的遗传学，这些主题与西弗吉尼亚州和全国都至关重要。ABI 3500xL基因分析仪将确保提供教育和培训机会，以培养能够应对紧迫的环境、医疗和生态挑战的多样化和高素质劳动力。WVU是一个充满活力，富有成效的跨学科研究社区的所在地，其中包括来自不同学科的遗传研究工作，包括生物化学，植物生物学，进化和物种形成，生态学，野生动物保护，传染病，微生物学，气候变化，药理学和生理学。WVU基因组学和生物信息学核心设施（WVU- gbcf）提供高质量、经济、高效的DNA测序、片段分析和细胞系认证服务，这些服务对WVU遗传和基因组相关工作的成功至关重要。此外，WVU-GBCF支持该地区和整个州的几所依赖DNA测序和咨询服务的大学。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

An award is made to West Virginia University (WVU) to replace and upgrade the existing Applied Biosystems 3130xL genetic analyzer with the ABI 3500xL, allowing enhancements to the current services provided by the WVU Genomics and Bioinformatics Core Facility (WVU-GBCF). Specifically, this replacement will improve turn-around time, result in higher quality output, and create the capacity for multiplexing, all of which will strengthen ongoing local and regional research and teaching efforts. As the state of West Virginia’s land grant institution, WVU and the WVU-GBCF are committed to providing training and support at both the university and statewide levels. There is strong interest in general genomics-related research and coursework, and as such, the WVU-GBCF provides numerous cutting-edge hands-on educational and training opportunities for students from all WVU campuses and the greater Appalachian region. Specifically, the facility provides training, troubleshooting, and services for students and instructors where DNA sequencing and/or fragment analysis is conducted as part of undergraduate laboratory courses. Moreover, the capabilities and resources provided by the WVU-GBCF are central to numerous undergraduate and graduate student thesis and dissertation projects ranging from the genomic responses to climate change in agronomically important crop plants to the genetics of opioid and psychostimulant abuse, topics of vital relevance for both West Virginia and the nation. The ABI 3500xL genetic analyzer will ensure the provision of educational and training opportunities in the development of a diverse and well-qualified workforce capable of confronting pressing environmental, medical, and ecological challenges.WVU is home to a vibrant, productive, and interdisciplinary research community, with genetic research efforts from a diverse set of disciplines including biochemistry, plant biology, evolution and speciation, ecology, wildlife conservation, infectious disease, microbiology, climate change, pharmacology, and physiology. The resources available at the WVU Genomics and Bioinformatics Core Facility (WVU-GBCF) provide the high-quality, affordable, and efficient DNA sequencing, fragment analysis, and cell-line authentication services that are crucial to the success of genetic and genomic-related efforts at WVU. Further, the WVU-GBCF supports several universities in the region and across the state that rely on DNA sequencing and consultation services.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.