Stimuli-Responsive Microcapsules for Transport, Controlled Delivery and Release of Metal Ions and Organic Chemical Mediators (B04)

常规的生物测定在溶液中以平均浓度应用化学介质。这绝不是在接近自然的情况下，在生产生物体周围出现局部浓度最大值。该项目旨在设计对pH值变化和光照敏感的负载聚合物微胶囊。它们将作为具有空间分辨率的化学介质的点源，并将模拟化学活性微生物，通过释放代谢物来塑造其直接环境。这些胶囊将在CRC内部的几个合作项目中应用和评估。

Conventional bioassays apply chemical mediators in average concentrations in solution. This is by no means in a close to natural situation where local concentration maxima around producing organisms appear. The project aims for the design of loaded polymeric microcapsules which are responsive to pH changes and illumination. They will act as point-sources for chemical mediators with spatial resolution and will mimic chemically active microbes that shape their immediate environment through the release of metabolites. The capsules will be applied and evaluated in several collaborations within the CRC.