Spatio-temporal specificity of cambium stem cell signaling (B12)

植物芽和根的径向生长对木材和大型植物体的形成至关重要，因此对生物量的产生至关重要。这一过程取决于一组被称为形成层的干细胞的组织形成特性，形成层产生次生维管组织（木材和韧皮）。我们现在将利用形成层的独特特征来建立植物及其他干细胞生态位组织的一般原则。为此，我们将验证一种假设，即在形成层区域内通过植物激素孤盏孤内酯（SL）对信号的时空调节对植物径向生长过程中组织的有组织生产至关重要。在与B01项目的密切合作中，我们将特别研究干细胞特异性同源盒转录因子WOX4和WUS在促进SL信号传导中的作用，作为植物干细胞系统的一个基本特征。

Radial growth of plant shoots and roots is essential for the formation of wood and of large plant bod-ies, and thus for the creation of biomass. This process depends on the tissue forming properties of a group of stem cells called the cambium, which produce secondary vascular tissue (wood and bast). We will now leverage the unique features of the cambium to establish general principles of stem cell niche organization in plants and beyond. To this end, we will test the hypothesis that a spatio-temporal modulation of signaling through the plant hormone strigolactone (SL) within the cambium domain is essential for an organized production of tissues during radial plant growth. In close collaboration with project B01, we will in particular investigate the role of the stem cell-specific homeobox transcription factors WOX4 and WUS in promoting SL signaling as one essential feature of plant stem cell systems.