Function and modulation of the protein quality control network in mammalian mitochondria

该项目在生物技术和分子医学领域具有潜在的技术效益，特别是在与年龄有关的细胞退化方面。作为我们研究成果的结果，可以制定策略来推迟与线粒体功能障碍相关的疾病的发病或降低其严重程度。培训未来的研究科学家是我们研究计划不可分割的一部分，我们与该领域的世界领导者的合作为人员、思想和新兴方法的交流提供了极好的机会。该项目将在这一领域处于领先地位，从而扩大澳大利亚在科学进步前沿的声誉。

This project has potential technological benefit in the areas of biotechnology and molecular medicine especially in relation to age-related cellular degeneration. As a result of our research outputs, strategies could be developed to either delay the onset or reduce the severity of diseases related to mitochondrial dysfunction. Training research scientists of the future, forms an integral part of our research program and our association with world leaders in the field provide excellent opportunity for exchange of personnel, ideas and emerging methodologies. This project will lead the way in this field and consequently will expand Australia's reputation at the forefront of scientific advancement.