Isoporphyrins

该项目的目标是发展异卟啉的化学，基于我们最近发现这些化合物的更好的获取。在建议的期限内，将处理两个主要问题：1。荧光锌异卟啉衍生物的研究本部分主要研究了荧光锌异卟啉衍生物的光学性质和溶解性，并对荧光锌异卟啉衍生物与细胞系统的相互作用进行了研究.异卟啉配体配位化学的研究进展本部分研究了迄今未知的3d元素金属异卟啉配体的制备、氧化还原化学和金属反应性。

The project aims towards the development of the chemistry of isoporphyrins, based on our recent finding of an improved access of these compounds. Two major issues are to be dealt with during the term of the proposal:1. Development of fluorescent zinc isoporphyrin derivatives This part focusses on optimizing optical properties and solubilities of zinc isoporphyrins for interactions with cellular systems.2. Development of the coordination chemistry of isoporphyrin ligandsIn this part the preparation, redox chemistry and metal based reactivity of hitherto unknown metal isoporphyrins of the 3d elements are investigated.