Analysis of the biomechanics of the wrist joint in the context of surgical therapy planning

目前尚缺乏对八块腕骨的载荷传递和运动行为的基本了解，这八块腕骨由复杂的软组织装置连接，共同支持中手相对于下臂的运动。因此，手腕的手术治疗是基于外科医生的个人经验，治疗结果差异很大。本课题的目标是建立一种有效的人体腕关节多体仿真模型，用于解决人体腕关节的逆动力学和正动力学问题。在开发腕关节模型的过程中，将使用不同的方法对测量的骨骼运动行为进行调查和建模，并使用表面模型来建立腕骨之间运动和载荷传递的特征信息。这将首次将体内和体外研究不同腕骨运动行为的优势结合起来。跨学科的方法(医学、生物力学)保证了有效性和医学相关性。随着先进的测试设备和先进的检查方法的发展，将有机会对生理学以及病理和手术改良的手腕关节进行检查。因此，首次基于客观标准对手术干预措施进行模型支持的比较是可能的。

The fundamental understanding of load transmission and motion behavior of the eight carpal bones, which are connected by a complex soft tissue apparatus, and altogether support the movement for the middle hand against the lower arm, is currently missing. Therefore, surgical therapies of the wrist are based on the individual experience of the surgeon, and the therapeutically results vary strongly. The goal of this project is a valid multi-body-simulation model of the human wrist joint for the solution of the inverse-dynamic and forward-dynamic problem. During developing of the wrist joint model, there will be used different methods for the investigation and modeling of the measured bony motion behavior and the surface models to establish characteristic information of the motion and load transmission between the wrist bones. For the first time the advantages of in vivo and in vitro investigation of the motion behavior of the different wrist bones will be combined. The interdisciplinary approach (medicine, biomechanics) guarantees the validity and medical relevance. With the developed test setup and the developed investigation methods there will be the chance to investigate physiologically and also the pathologically and surgically-modified wrist joints. Thus, for the first time a model-supported comparison of surgical interventions will be possible based on objective criteria.