Development of compact fluorescence polarization measurement devices

研制了一种紧凑型荧光偏振测量系统，用于分析生物分子之间以及生物分子与药物之间的相互作用。在这项研究中，我们开发了一种使用光纤和洗液棱镜的紧凑型荧光偏振检测装置和一种使用液晶显示器和CCD探测器的系统，并对其性能进行了评估。从这些评估中，两人都能够确认荧光偏振测量是可能的。研制的装置和系统易于小型化，实现了一种价格低廉、结构紧凑的荧光偏振测量装置。

Compact fluorescence polarization measurement systems for analyzing the interaction between biomolecules and between biomolecule-drug was developed. In this study, we developed a compact fluorescence polarization detection device using fiber optics and a lotion prism and a system using a liquid crystal display and a CCD detector, and evaluated these performances. From these evaluation, both were able to confirm that fluorescence polarization measurement was possible. The device and system developed here can be miniaturized easily, and these achievements lead to the realization of a cheap compact apparatus for fluorescence polarization measurement.