Role of the aryl hydrocarbon receptor in hepatic immune regulation (P03*)

芳香烃受体(AhR)是一种重要的免疫调节剂，可以将环境、微生物或代谢配体的信号整合到免疫反应中。我们将从T细胞和肝脏抗原提呈细胞水平探讨AhR在调节肝脏免疫耐受和炎症中的作用。此外，我们将评估AhR配体在治疗炎症性肝病方面的治疗潜力。

The aryl hydrocarbon receptor (AhR) is an important immune modulator that can integrate signals from environmental, microbial or metabolic ligands into the immune response. We will explore the role of AhR in the regulation of hepatic immune tolerance and inflammation, both at the level of T cells and hepatic antigen presenting cells. Furthermore, we will evaluate the therapeutic potential of AhR ligands for the treatment of inflammatory liver diseases.