Multiple Quantum Coherence NMR and its Application to Molecular Structure Study.

我们发展了利用多量子相干的核磁共振方法，并将其应用于分子结构的研究。发展了多中继相关谱，其中一个自旋的单量子相干被转移到远离四个键的其他自旋。将该方法应用于纤维低聚糖的分析。结果表明，该方法对分离出各单糖单元非常有用。发展了双量子相干回波相关光谱(DECSY)。将1H法应用于聚乙烯醇，测定了不同立体规整度序列中的当量亚甲基质子。该方法还用于测定环氧丙烷的立构规整度，鉴定聚丁二烯的顺式和反式基团。利用多量子滤光片分离出双自旋系统。双量子滤光片使纯相COSY成为可能。将带有三量子滤光片的COSY用于聚乙烯醇的当量亚甲基质子的测定。

We developed the NMR method utilizing the multiple quantum coherence and applied it to the study of molecular structure. The multiple-relay correlation spectroscopy in which the single quantum coherence of a spin is transferred to other spins far apart four bonds was developed. This method was applied to cellooligosaccharides. It was found that this method is quite useful to separate out each single saccharide unit. Double quantum coherence echo correlated spectroscopy(DECSY) was developed. This method of 1H was applied to poly(vinyl alcohol) to determine equivalent methylene protons in the sequence of different stereoregularity. The <^(13)C> version of this method was also applied to the determination of stereoregularity of polypropylene oxide and the identification of cis and trans units of polybutadiene. Multiple quantum filter was utilized to separate out the two-spin system. Pure phase COSY became possible with double quantum filter. COSY with triple quantum filter was applied to poly (vinyl alcohol) to determine equivalent methylene protons.