Intracranial pressure controlling system with servomechanism

众所周知，颅内压升高在严重闭合性颅脑损伤、脑血管意外急性期和脑肿瘤的病理生理和预后决定中起着重要作用。为了治疗颅内异常高的颅内压，挽救生命，提高颅内急症的治疗效果，我们研制和改进了带伺服机构的自动颅内压控制器。本系统的主要结构由颅内压监测仪、连接脑减压器输注器的开关、血压、心率、阻抗气描图和潮末呼气co2同步监测组成。我们研究中最重要的问题是如何确定颅内压设定点的条件，我们认为20mmHg是最安全的，25mmHg是上限，当必须超过30mmHg时，必须考虑其他减压方式，如紧急脑室液引流。我们的装置被发现用于指示后一过程的时间。为了获得这些压力情况，我们进行了动物实验研究，使用诱发电位法监测脑区域血流量，并在临床情况下谨慎安全地尝试了该方法。

It is well known that the increase of intracranial pressure plays the important role in pathophysiology and determination of outcome in cases of severe closed head injury, acute stage of cerebrovascular accident and brain tumor.We have developed and improved our automatic intracranial pressure controller with servomechanism, in order to treat the abnormally high intracranial pressure to save the life and to improve the outcome of those intracranial emergency.Main structure of our system is composed of an intracranial pressure monitor, the on-and-off switch connected the infuser of brain pressure reducer, as well as simultaneous monitoring of blood pressure, heart rate, impedance pneumograph and end-tidal expired CO_2.The most important problems of our study is how to determine the condition of setting point of intracranial pressure and we concluded that 20mmHg to be safest, 25mmHg to be upper limit and when it has to be more than 30mmHg, one must consider the other way of relief the pressure such as emergency cerebral ventricular fluid drainage.our device is found useful to indicate timing of the latter procedure. In order to obtain these pressure condition, we have done animal experimental studies, using evoked potential method monitoring regional cerebral blood flow as well as we tried this method on clinical situations carefully and safely.