SFB 1411: Design of particulate products

CRC 1411的长期愿景是颗粒产品的预测设计，即具有控制尺寸，形状和成分的颗粒系统。这一目标将通过两步走的方法来实现。首先，建立描述结构-性质函数的预测模型，并用于优化特定目标函数（即期望的产物性质）所需的粒子结构。其次，一组描述工艺结构函数的预测模型随后确定了优化的工艺条件，以制造具有所需结构的粒子系统。这一挑战由四个紧密相连的研究领域（RAs）来解决，重点是颗粒形成（RA A），它们的色谱分离（RA B），综合表征（RA C）以及建模和优化（RA D）。在第一个资助期内，CRC 1411在颗粒产品的针对性预测设计方面取得了重大进展。这些科学突破是使用相对良好的模型系统实现的，例如各向同性颗粒，尺寸排除色谱，或薄膜颗粒排列的结构优化。在成功地建立了一般方法、基础设施和合作之后，CRC 1411现在完全可以解决几个步骤变化。在第二个资助期，我们将针对各向异性粒子系统的连续制造，它们的集成处理和建立强大的相互作用色谱方案，这有望增强NP分离能力。此外，分散性和非理想性在结构形成中的作用将是第二个资助期的一个新的中心动机。通过从根本上了解颗粒构建块的自组织，并通过探索结构不规则性如何影响着色或色谱分离中的功能特性，我们最终将能够减轻这种影响，并设计出具有优化性能的稳健过程。卓越的研究环境，包括Friedrich-Alexander-Universität erlangen - n<s:1> rnberg （FAU）的五个跨学科中心，杜伊斯堡-埃森大学（UDE）的纳米能源技术中心（NETZ）和亥姆霍兹可再生能源研究所（HI ERN），为CRC 1411提供了理想的平台。通过广泛的国际合作伙伴网络和一系列国际会议和研讨会，我们已经牢固地将CRC 1411建立为一个高度可见的颗粒产品设计研究中心。凭借现代化的跨学科综合研究培训小组，开创性的数据基础设施，支持性别平等和家庭友好型工作环境的一系列连贯措施，以及专门的外展项目，CRC 1411积极塑造粒子技术以及FAU和相关研究所的形象。

The long-term vision of CRC 1411 is the predictive design of particulate products, i.e., particle systems with controlled size, shape, and composition. This objective will be achieved by a two-step approach. First, predictive models describing structure-property functions are established and used to optimise the required particle structure for a specific target function, i.e., a desired product property. Second, a set of predictive models describing the process-structure functions subsequently determine optimised process conditions to fabricate particle systems with the desired structure. This challenge is approached by four strongly interlinked research areas (RAs), focussing on particle formation (RA A), their chromatographic separation (RA B), comprehensive characterisation (RA C), and modelling and optimisation (RA D). In the first funding period, CRC 1411 made significant progress towards the targeted predictive design of particulate products. These scientific breakthroughs were realised using comparatively well-behaved model systems, such as isotropic particles, size exclusion chromatography, or structure optimisation of particle arrangements as thin films. Having successfully established general methodologies, infrastructure and collaborations, CRC 1411 is now perfectly set to address several step changes. In the second funding period, we will target the continuous fabrication of anisotropic particle systems, their integrated processing and the establishment of powerful, interaction chromatography schemes, which promises enhanced NP separation capabilities. In addition, the role of dispersities and non-idealities in structure formation will be a central new motive in the second funding period. By fundamentally understanding the selforganisation of particulate building blocks across the scales and by exploring how structural irregularities influence functional properties in colouration or chromatographic separation, we will ultimately be able to mitigate such effects and design robust processes with optimised performance. The excellent research environment including five interdisciplinary centres at the Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), the NanoEnergieTechnikZentrum (NETZ) at the University of Duisburg-Essen (UDE) and the Helmholtz Institute for Renewable Energy (HI ERN) provides the ideal platform for CRC 1411. Evidenced by a broad network of international partners and a set of international conferences and workshops, we have firmly established CRC 1411 as a highly visible research centre for the design of particulate products. With the modern and interdisciplinary integrated research training group, a pioneering data infrastructure, a coherent set of measures supporting gender equality and a family-friendly working environment, and a dedicated out-reach project, CRC 1411 actively shapes particle technology as well as the profile of FAU and the involved institutes.