Cooperative Triazole H-Donors in Asymmetric Dearomatization by Anion-Binding Catalysis (A12#)

在本项目中，将探索手性四-三氮唑(TetraTri)结构作为C-H基中性阴离子受体在催化阴离子结合过程中的协同结合和反应活性。因此，自组织结构的影响和可控性、它们的主客体络合物(与一个或多个阴离子)以及结合的协作性性质将通过物理和分析方法进行研究，并辅之以量子力学研究。最后，展望了其在N-和O-杂芳烃对映体选择性阴离子键合有机催化脱芳构化反应中的新应用。

In this project, the cooperative binding and reactivity of chiral tetrakis-triazoles (TetraTri) structures as C-H-based neutral anion acceptors in catalytic anion-binding processes will be explored. Thus, the influence and the controllability of self-organized structures, their host-guest complexes (with one or more anions) and the cooperativity nature of the binding will be investigated by physical and analytical methods, complemented by quantum mechanical studies. Finally, novel applications in enantioselective anion-binding organocatalyzed dearomatization process of N- and O-heteroarenes will be developed.