Blood Pressure and Urinary Bisphenol A Concentrations After Soda Consumption from Cans

饮用罐装饮料是非常普遍的。汽水消费中最常接触的是含有双酚a的环氧树脂内衬罐。罐装苏打水对双酚A （BPA）暴露的影响很大，但尚未得到充分的研究。可口可乐的酸度很高，pH值为2.5，有利于环氧树脂衬里的BPA浸出。同样，由于罐头中的BPA含量，饮用罐装苏打水可能会使血压升高。鉴于人口中高血压的持续增加，这将具有重要意义。因此，我们建议进行一项随机单盲交叉干预试验，以评估饮用罐装可口可乐后尿液中的BPA浓度，以解决这些重要问题。

Consumption of beverages from cans is extremely common. Soda consumption is the most frequent exposure to Bisphenol A-containing epoxy resin lining of cans. The burden of Bisphenol A (BPA) exposure resulting from canned sodas is significant and has not been sufficiently studied. Coca-cola has a high acidity level with a pH of 2.5 fostering BPA leaching from the epoxy lining. Similarly, canned soda consumption may raise blood pressure due to the BPA content of cans. This would have significant implications given the continuing increase of hypertension in the population. We therefore propose to conduct a randomized single-blind cross-over intervention trial to evaluate urinary BPA concentrations after consuming coca-cola from cans to address these significant questions.