Stereotactic laser balloon hyperthermia treatment

为建立立体定向激光球囊热疗治疗深部恶性小胶质瘤的方法，报道了应用激光治疗机进行组织间热疗的实验研究。The Ultra Line^&lt；TM&Gt；光纤(贺利氏激光超音速公司)插入6F硅胶气囊导管。激光光纤横向传输激光束(80ﾟC)。用生理盐水充气气囊，使激光纤维周围的肿瘤组织处于低氧状态。这种状态意味着增强对肿瘤的热效应。激光功率为5W。计算机通过特定的参数编程，通过反馈控制在45ﾟC下维持远离激光光纤的10 mm组织温度。对大鼠皮下移植的胶质瘤进行45min的热疗。肿瘤热损伤区根据激光(厚度10 mm，角度100度)呈FUN形状进行检测。通过旋转球囊导管中的激光纤维，可以改变激光的方向，以扩大肿瘤的范围。

To establish the stereotactic laser balloon hyperthermia treatment for the deep seated small malignant glioma, the experimental study of the interstitial hyperthermia treatment using the Nd : YAG laser unit was reported. The Ultra Line^<TM> fiber (Heraeus Laser Sonics, Inc.) was inserted into the 6F silicone balloon catheter. The laser fiber transmits the laser beam laterally (80ﾟC). And the balloon was inflated with physiological saline to make the tumor's tissue around the laser fiber hypoxic state. This state means to enhance the thermal effect for tumorsThe laser power was 5W.The computer was programd with specific parameters to maintatin the 10 mm tissue temperature apart from laser fiber through feed back control at 45ﾟC.In this condition. 45 minutes hyperthermia treatment was done for the rat's implanted subcutaneous glioma. The thermal damaged area of the tumor was detected the fun-shaped according to the laser beam (10 mm thickness and 100 degree angle). And by rotating the laser fiber in the balloon catheter, the direction of the laser beam can be changed for the tumor's extention.