Study on the Mechanism of Subgingival Calculus Formation

在本研究中使用了Beetrode ^R和锑电极。随着结石指数0、1、2的增加，囊内pH值略有变化，但无显著性差异（r=0.21）。相反，当结石指数为3时，pH值下降。4名健康受试者的囊袋深度与囊袋pH值之间无显著相关性。袋深度1、2、3 mm的pH值范围很广，pH值为5.8至7.8。并且，4 mm的袋深度范围为pH 6.5至pH 7.4。5例碘缺乏病患者的牙周袋深度与牙周袋pH值呈直线正相关（r=0.54）。结果：牙周炎患者牙周袋内pH值较正常人偏碱性，并对患者唾液和龈沟液中的微粒进行了分析。龈沟液中多胺含量显著高于唾液。据报道，在纯唾液中未检测到多聚胺。因此，本研究中所检测的全唾液中的多聚胺可能是从龈沟漏出的。7例牙周病患者龈沟液中ALP活性（533.2 ± 273.1）高于唾液（203.1 ± 160.5IU/l），其中1例患者龈沟液中ALP活性（533.2 <plus-minus>± 273.1）高于唾液（203.1 <plus-minus>± 160.5IU/l），2例牙周病患者龈沟液中ALP活性（533.2 ± 273.1）高于唾液（203.1 ± 160.5IU/l）。

Beetrode ^R and antimony electrodes were used in this investigation. With increase the calculus index of 0,1,2 in the intrapocket pH slightly shifted without significantly (r=0.21). In cotrast, at the calculus index of 3 the pH value decreased. The significant relationship betweem pocket depth and pocket pH was not shown in 4 healthy subjects. The pH in the pocket depth 1,2,3 mm ranged widely pH 5.8 to pH 7.8. And, the pocket depth of 4mm ranged pH 6.5 to pH 7.4. However, in the ocasion of 5 per iodontal patients, the relationship between pocket depth and pocket pH showed positive linear relation (r=0.54). The pH in the periodontal pocket in the patients ranged more alkaline than the healthy subjects.The poliamiens in saliva and GCF in the patients were analized. The amounts of poliamines in GCF were significantly greater than that in saliva. It has been reported that the poliamines are not detected in pure saliva. So, the poliamines in whole saliva detected in the present study must be leaked from gingival sulcus. Furthermore, the positive relationship was observed between the amount of poliamines and the pH in the pocket.The activities of ALP in GCF (533.2<plus-minus>273.1) were higher than that (203.1<plus-minus>160.5IU/1) of saliva in 7 periodontal patie