Dynamics in dense mixtures: Kinetics versus thermodynamics in non-equilibrium fluctuations, phase separation and structure formation

非平衡弛豫是实验物理学和理论物理学中一个重要的基本现象。对于密集的多组分混合物尤其如此，这种混合物在自然界中无处不在——在细胞质等生物流体中——以及在软物质中——例如在胶体悬浮液中。已经处于平衡状态的混合物由于分馏而表现出复杂的相行为，其中不同类型的颗粒在相之间不均匀地分配自己。非平衡过程，如淬火后的相分离，继承了所有这些热力学复杂性，但包含动力学效应作为一个更重要的因素。这些由连续介质方法中的迁移率描述的动力学效应在密集系统中具有重要的结构，因为例如，不同粒子在相反方向上的运动可能比集体粒子运动慢得多或快得多。这可能导致新的现象，如在相分离中出现多时间尺度和长寿命的非平衡结构，这些才刚刚开始探索。该项目将从理论上研究致密混合物的动力学，以解决该领域的许多开放挑战。它的主要新颖之处在于将胶体和生物混合物的极限情况与它们截然不同的热力学联系起来，并研究了稠密、缓慢混合物中可能发生的非平凡动力学。通过这种方式，该项目旨在通过解决一些关键的开放性问题来实现我们对致密混合物物理学的理解的一步改变，同时开发新的方法，例如系统推导流动性，这将为未来广泛的工作开辟道路。这项雄心勃勃的研究计划要求，并明确地设计为利用这两个pi为项目带来的独特的专业知识组合。这些方法包括用于非平衡液体的粗粒化技术和连续体方法（M. kr<s:1> ger）以及用于大混合物相分离的投影方法（P. Sollich）。

Non-equilibrium relaxation is an important phenomenon of fundamental interest in experimental and theoretical physics. This is especially so for dense multi-component mixtures, which are ubiquitous in nature -- in biological fluids such as the cytoplasm -- as well as in soft matter -- for example in colloidal suspensions. Already at equilibrium such mixtures exhibit complex phase behaviour due to fractionation, where particles of different type partition themselves unevenly between phases. Non-equilibrium processes such as phase separation after a quench inherit all of this thermodynamic complexity but contain kinetic effects as a further important ingredient. These kinetic effects, which are described by mobilities in continuum approaches, carry significant structure in dense systems because e.g. movement of different particle species in opposite directions can be much slower or faster than collective particle motion. This can lead to novel phenomena like the emergence of multiple timescales and long-lived non-equilibrium structures in phase separation, which have only begun to be explored.This project will study the dynamics of dense mixtures theoretically to address the many open challenges in this area. Its main novelty lies in connecting the limiting cases of colloidal and biological mixtures with their rather different thermodynamics, and in studying the non-trivial kinetics that can occur in dense, slow mixtures. In this way the project aims to achieve a step change in our understanding of the physics of dense mixtures, by tackling a number of key open questions, while at the same time developing new methodologies for e.g. the systematic derivations of mobilities that will open the way for a broad range of future work. The ambitious research plan requires, and is designed explicitly to exploit, the unique combination of expertise that the two PIs bring to the project. These include coarse-graining techniques and continuum approaches for non-equilibrium liquids (M. Krüger) and projection methods for phase separation in large mixtures (P. Sollich).