Biomedical Informatics Support Platform (BISP) - provides IT structures and pipelines to store, exchange and integrate the numerous phenotypic, genomic and functional data generated in SP1-7 and CP1.
Biomedical Informatics Support Platform (BISP) - provides IT structures and pipelines to store, exchange and integrate the numerous phenotypic, genomic and functional data generated in SP1-7 and CP1.
批准号:
441000909
负责人:
Professor Dr. Tim Beißbarth
金额:
$0.0万
依托单位国家:
德国
项目类别:
Clinical Research Units
财政年份:
--
资助国家:
德国
项目状态:
未结题
起止时间:
中文摘要
在CRU 5002的框架下,CP2的生物医学信息学支持平台(BISP)负责提供IT结构和管道,以存储、交换和集成在SP1-7和CP1中生成的大量表型、基因组和功能数据,并将它们与MolPAC计划中收集的全面临床注释合并。此外,这一核心项目将对整个联盟所需的所有基因组分析进行下一代测序研究,并将对CP1中建立的翻译PDAC模型进行转录组分析。此外,CP2将为所有科学子项目提供统计咨询,以便有意义地规划和执行他们的基因组实验。此外,CP2负责执行全面的生物信息学分析和对基因组数据的合格解释。最后,CP2将整合CRU 5002内收集的分子亚型数据与PDAC亚组的公布数据,并将支持CP1比较PDAC PDX模型和有机物的亚型一致性。
英文摘要
In the framework of the CRU 5002 the Biomedical Informatics Support Platform (BISP) of CP2 accounts responsible for providing IT structures and pipelines to store, exchange and integrate the numerous phenotypic, genomic and functional data generated in SP1-7 and CP1, and to merge them with the comprehensive clinical annotations gathered in the MolPAC program. Further, this core project will conduct Next-Generation-Sequencing studies for all genomic analyses required throughout the consortium and will perform transcriptome analysis of translational PDAC models established in CP1. In addition, CP2 will offer statistical consulting to all scientific subprojects for the meaningful planning and execution of their genomic experiments. In addition, CP2 is responsible for the execution of comprehensive bioinformatic analyses and the qualified interpretation of genomic data. Finally, CP2 will integrate molecular subtyping data collected within the CRU 5002 with published data on PDAC subgroups and will support CP1 in comparing PDAC PDX-models and organoids for their subtype consistency.
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Bioinformatics approach to establish a new graph-based Wnt model for metastasis formation in breast cancer
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批准号:197931384
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项目类别:Research Units
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资助金额:$0.0万
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财政年份:2011
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负责人:Professor Dr. Tim Beißbarth
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依托单位:
Development of statistical and computational methods, tools, and infrastructure as well as data analysis, data management, and support for clinical researchers
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批准号:50725709
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项目类别:Clinical Research Units
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资助金额:$0.0万
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财政年份:2007
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负责人:Professor Dr. Tim Beißbarth
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依托单位:
(Weiter-)Entwicklung und Bewertung statistischer Methoden zur Analyse von regulatorischen Netzwerken in großen Genexpressionsdatensätzen
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批准号:5393364
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项目类别:Research Fellowships
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资助金额:$0.0万
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财政年份:2002
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负责人:Professor Dr. Tim Beißbarth
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依托单位:
海外基金